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Young Woman's Health Care

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Women are often surprised that we do provide "routine" gynecologic care—although we feel that there is nothing "routine" about it.

Aside from our special interests in hysteroscopic surgery and abortion services, the majority of our practice time is devoted to a variety of gynecological services. These include annual examinations (including pap smears), STD testing, contraceptive counseling (including permanent sterilization), management of abnormal pap smears (including colposcopy and LEEP procedures), infertility, as well as the management of a host of other gynecologic problems including abnormal menstrual bleeding, uterine fibroids, ovarian cysts, premenstrual disorders, sexual dysfunction and menopause management. We often provide primary care to our patients who require preliminary management hypertension, hypercholesterolemia as well as diseases of the breast.


             Pap smears, HPV testing and HPV Vaccines













                          



                        

                                 

A Pap smear involves the painless removal of cells from the cervix


You and Your Pap smear

A Pap smear involves the painless removal of cells from the cervix

What is the Pap smear?

The Pap smear is a screening test for cervical cancer. The cervix is the lower part of the uterus and the entry to the birth canal. Despite what most women think few women die in the United States each year because of cervical cancer. You may know a friend who had a pap smear showing a pre-cancerous condition of the cervix, known as dysplasia. You may even know a woman who had a condition called carcinoma in situ of the cervix, but these abnormalities are not life threatening as long as a woman is under a doctor's care and doesn't ignore the condition.

The Pap smear was developed by Dr. George Papanicolaou in 1954. This painless technique has been responsible for saving tens of millions of lives world-wide since its use became popularized. The Pap smear is nothing more than an exam, by a health care provider, that involves the gentle brushing and removal of cells from the cervix to be examined under the microscope by a trained cytologist.

If you're reading this you may be a woman trying to learn more about Pap smears or you might be someone who recently found out that she has an abnormal pap smear. Before we get started let's put things into perspective about cervix cancer. In year 2005 the American Cancer Society reported that 662,870 women in the United States died of all forms of cancer. It breaks down as follows:

  • Lung cancer deaths                  79,560
  • Colon cancer deaths                 56,660
  • Breast cancer deaths                 40,410
  • Rectal cancer deaths                 16,810
  • Ovarian cancer deaths              16,210
  • Pancreatic cancer deaths          16,080
  • Leukemia deaths                        10,030
  • Lymphoma deaths                       9,680
  • Uterine cancer deaths                 7,310
  • Multiple myeloma deaths           5,640
  • Stomach cancer deaths               4,780
  • Kidney cancer deaths                 4,640
  • Bladder cancer deaths                 4,210
  • Cervical cancer deaths                3,710
  • Esophageal cancer deaths          3,300
  • Melanoma deaths                        2,860

For more information on the risk of various cancers in women visit

http://www.cancer.org/downloads/STT/CAFF2006PWSecured.pdf

You can plainly see that although many women are afraid of cervical cancer very few women, comparatively die of this diseaser. That's why the National Institutes of Health lists cervical cancer as a rare disease (remember I'm not talking about carcinoma in situ which is almost 100% curable, and is different from invasive cervical cancer!).

This is wonderful news and it means that visiting your health care provider regularly is tremendously important. Most of the women in the US who die of cervical cancer did not get regular pap smears! So, before you read any further understand that the Pap smear, which has been around for over 50 years, has made invasive cervix cancer a rare disease and death from cervical cancer rarer still!

The last point I'd like to make about Pap smears is that they are a screening test and not a definitive diagnosis. Pap smears help the health care provider determine which women need specific diagnostic tests such as colposcopy and cervical biopsies. If a pap smear indicates need to that a woman needs further diagnostic tests the actual diagnosis will require a biopsy.

So, exactly what is the cervix? What does it do? What is it made of?


The cervix is the lowest portion of the uterus. It can be seen through the vagina with the use of a vaginal speculum. During pregnancy the cervix acts as a valve and keeps the uterus from opening until a child is mature enough to be born. During labor the cervix opens to about 10 cms (4 inches) and allows the baby to enter the birth canal.

The cervix is covered with a thin skin called "epithelium". It is a smooth surface very similar to the type of tissue that covers the inside of your lip.

The cervix represents an area where two types of epithelium (think of this as similar to skin cells) join. The "skin" of the cervix is covered with cells called squamous cells


                                                         
Squamous cells (stacked like omelets)       Columnar cells (bunch of beer cans)

Squamous cells look like "omelets" stacked up 6 or 8 deep. The "skin" of the inside of the uterus is made up of columnar cells (think of these as being arranged like a column of beer cans). The cervix contains a vulnerable area where these two cells types join. This area is called the squamo-columnar junction or transition zone (T-Zone) and represents the changeover from one cell type to another. THE IMPORTANT PART to know is that it is specifically in the squamo-columnar junction or transition zone that cancer occurs.                               



When should I get my first pap smear and how often should I get one?

The American Cancer Society recommends that you get your first pap smear at age 21 or within 3 years of becoming sexually active---whichever comes first.

Since the Pap smear has been adopted over 50 years ago, this country has seen a sharp decline in the number of women suffering from invasive cancer of the cervix. Pap smears are performed annually. Women over the age of 50 may not need pap smears annually but they be seen annually by their health care provider as other cancers become more prevalent in post-menopausal women.

Modern pap smears are both painless and accurate. The cells that are obtained can be tested to see if they are abnormal in appearance and even for the presence of cancer-causing viruses.

How common are Pap smear abnormalities?

About 55 Million Pap smears are performed in the United States each year. 3.5 Million of these Pap smears or 6% are abnormal and will require medical follow up. So just to put things in perspective remember that there are approximately 3700 cervical cancer deaths in this country each year. So, for every death attributed to cervix cancer there are 1000 abnormal pap smears! Calm down….you're not alone if you have an abnormal pap smear.

What are the risk factors for Pap smear abnormalities and specifically for pre-cancerous changes?

The major risk factors for Pap smear abnormalities are:

  • Having sex at an early age (before 18)
  • Having sex with multiple sexual partners
  • Having sex with someone who has had multiple partners
  • Having sex with uncircumcised men
  • A history of Chlamydia infection
  • Obese women
  • Multiple pregnancies
  • Smoking
  • The HPV Virus
  • A family history of cervical cancer

What are the types of abnormalities that a pap smear can detect?

Pap smear abnormalities cover a range from the very mild to those that are of far greater concern. Before we can discuss pap smears, however, we need to discuss (a) the range of cervical cell abnormalities and (b) what these abnormalities look like on a tissue biopsy.

The Pap smear is NOT a biopsy, however. Instead, it takes a sample of cells that are normally shed by the cervix and let's the health care provider know when a biopsy might be necessary. The definitive diagnosis of an abnormality is made with a biopsy. Now here's a photomicrograph of what a cytologist might see when looking at an abnormal cell.

                                                  
                                               
Pap smear showing large abnormal cells

Based on these Pap smear readings the cytologist will sometimes recommend further studies, including colposcopy and biopsy.

I. ASCUS (Atypical Squamous Cells of Undetermined Significance)

The very mildest abnormalities detected on Pap smear are referred to as ASCUS (atypical typical squamous cells of undetermined significance). This term is used for reporting Pap smear findings and indicates that some flat (squamous) cells look unusual and may or may not be pre-malignant. Of all Pap tests that reveal ASCUS reading, 80-95% are caused by benign conditions, chiefly infections. The remaining 20% prove to be precancerous when further testing, such as a colposcopy is performed.

In general, women and their gynecologists find this category the most annoying. The vast majority of these are "it's probably normal but I want to keep an eye on things". Women become concerned that they're harboring invasive cancer---which is virtually never the case. Gynecologists would rather tell a woman "it's completely normal and you can return next year". Most women whose Pap smear reveals ASCUS are best managed by repeating the smear in 3-6 months or performing an additional test called a colposcopy (See below). In general, the best treatment for ASCUS is observation combined with colposcopy, since most of these lesions will spontaneously disappear without treatment. Some cases that co-exist with a vaginal or cervical infection will require antibiotic treatment.

As I've already stated, a pap smear that reveals ASCUS should not be ignored as some of them, on closer examination will reveal a more significant lesion. However, once that additional test has been performed, and dysplasia has been ruled out, this abnormality can be safely watched with repeat pap smears and occasional colposcopies—they do clear up given a little time and patience.

One of the "dangers" of ASCUS is that it tends to make women anxious and they often lose sleep—especially after talking to a friend whose well-intended advice often amplifies her anxiety. Unfortunately, many women hear the words "you have an abnormal pap smear" and insist on aggressive surgery. This is generally not recommended and often produces more problems that it solves.

II. The Dysplasias (Cervical Intraepithelial Neoplasia)

"Plasia" means growth. Dysplasia refers to the disorganized growth of cervical epithelial cells. But before we discuss disorganized growth we should look at what "organized" or "normal" growth looks like. If we look at the left hand portion of the picture just below,       


Graphics provided by Dr. Paul D. Indman you may visit his site WWW.gynalternatives.com

we can see that the bottom layers of cells are plump and contain nuclei. The top layer of cells is flat (like an omelet) and contains either small or no nuclei. Additionally, the cells are small and do not take up much stain.

The middle portion of the drawing reveals the appearance of dysplastic cells.                    


Notice that the cells at the bottom are darker (they take up more stain) and the nuclei are very large compared to the cytoplasm of the cell. This is disordered (or dysplastic) growth and can be categorized as "mild" "moderate" or "severe". When the disordered growth occupies the lower third of cervical "skin" or epithelium we consider it "mild". It is considered moderate when dysplasia occupies the lower half of the epithelium and when dysplasia occurs in the full thickness of the cervical epithelium we call it carcinoma in situ (CIS).

Many women in the U.S. have carcinoma in situ (or severe dysplasia). However this is almost 100% curable and is not the same as invasive cervical cancer, which is very dangerous and fortunately very rare. In carcinoma in situ (CIS) the full thickness of the epithelium has abnormal cells but they do not invade into the underlying tissue.                       


Invasion into the surrounding tissue is what defines a true cervical cancer.
             


To try and get an understanding of this try rubbing the skin on the back of your hand and notice that it is free of the underlying muscle and tendons---it moves freely with only gentle rubbing. If the entire thickness of that skin were affected with abnormal cells it would be called CIS. If the entire thickness of that skin were rubbed and found to be attached to underlying muscle and tendons that would be an example of invasive cervix cancer.

III. The Bethesda Classification System

The current method of classification of Pap smear abnormalities is known as the Bethesda System. Under this classification, moderate and severe dysplasias are combined into a single classification known as high grade squamous intraepithelial lesions (HSIL). What used to called "carcinoma in situ" is now considered part of the HSIL classification.

Mild dysplasia is also referred to as LSIL (low grade squamous intraepithelial lesion). Researchers believe that most of these lesions are caused by a less aggressive HPV type. The majority of these lesions spontaneously regress.

What is the relationship between Human papillomavirus (HPV) and cervical dysplasia and cancer?

HPV is a very common virus that causes papillomas or warts. There are over100 different types of HPV that affect the skin surface as well as various mucous membranes. Certain types can cause warts on the hands and feet (plantar warts). Additionally, there are about 30 types of HPV strains that cause venereal warts--also known as condylomata accuminata—as well as pre-cancerous and cancerous lesions of the cervix, vagina and vulva. In addition, other papillomas viruses cause warts in the throat and around the anus.

This is an electron photomicrograph of a type of human papillomavirus (HPV). You should visit www.hpvfaq.com and www.cancer.gov/cancertopics/factsheet/Risk/HPV for additional and helpful information regarding HPV.
 
                                                       
                                                            
 Electromicrography of HPV

HPV is very common. An estimated 5.5 Million cases are diagnosed each year making it responsible for about 1/3 of all STD infections in the US. Several quick facts about HPV

  • It is acquired through skin to skin contact—not through fluids
  • It can remain dormant for a very long time (years) making it possible for the virus to spread from one partner to the next without any warning such as visible lesion.
  • Most people with HPV don't know they have the virus—it is asymptomatic.
  • At any given time about 20 Million men and women in the US have an active HPV infection.
  • Nearly ¾ of Americans ages 15-49 have been infection with HPV in their lifetimes
  • Some types of HPV (6, 11, 42, 43, 44) cause genital warts
  • Some types of HPV (16, 18 and less commonly 31, 33, 35, 39, 45, 51, 52, ,56, 58, 59, 68 and 69) cause cervical dysplasia.

We know that the majority of cervical cancer and genital warts is caused by certain strains (6, 11, 16 and 18) of the human papillomavirus (HPV). These viruses are responsible for about 70% of all HPV infections in women.

As of 2006 the FDA has even approved the use of Gardasil, a vaccine to prevent some of the more harmful HPV infections. We are happy to discuss this vaccine to determine if it is right for you. Gardasil may prevent infection from HPV types 6, 11, 16 and 18. While it is helpful it is certainly not a guarantee that you will never develop an HPV infection.

What is colposcopy?

A colposcopy is nothing more than a procedure where the cervix is viewed through a magnifying lens after being stained with a dilute vinegar (acetic acid) solution. It is a painless procedure.
                                 

The photograph below reveals the cervical "os" or opening of the cervical canal. There are several areas of the SCJ or squamo-columnar junction that are visible. This is precisely where one type of epithelium, squamous (think omelets), transitions to another type of epithelium—columnar (think beer cans). Occasionally an abnormal area shows up as unusually "white". These areas are called "aceto-white" epithelium or AW. These AW areas are often where dysplasia can be found.

                             

      Example of mild dysplasia                    Example of severe dysplasia

What is a LEEP or a LLETZ Procedure?

LEEP stands for Loop Electosurgical Excision Procedure. Some doctors use the term LLETZ (Large Loops Excision of the Transformation Zone) which is an identical procedure.

This procedure is done, following a colposcopy which tells the physician exactly how large and where the lesion is located. The tissue is then submitted to a pathologist who examines the entire lesion looking for the presence of dysplasia and cancer. Additionally, the pathologist can tell if the entire lesion has been removed.

Although the LEEP procedure is a surgical procedure it is safely performed in our office. Many patients are given a combination of medications that result in conscious sedation—a type of "twilight sleep".


During this procedure an electrical energy generator is attached to a fine wire loop that when energized, functions as a precise and rapid surgical tool. This instrument is then directed toward an abnormal area on the cervix and may be used quickly, effectively and painlessly to remove the abnormal tissue. The procedure takes about 15 minutes to perform and you may expect to spend another 40 minutes in the office as your medications wear off.



How long is the recovery?

Most women return to work in 1-3 days. You should avoid heavy lifting for 3-4 weeks afterwards. You should avoid intercourse for a full 6 weeks postoperatively.

How effective is it?

LEEP is extremely effective, with a 90% success rate; however, there are cases in which the procedure has to be repeated.

What are the risks and consequences?

The risks and consequences are rare, but an LEEP can cause damage to the other pelvic organs or the wall of the vagina. There can be excessive bleeding or pelvic infection (particularly if you have sex before the recommended 3-6 weeks for the cervix to heal.) There also can be a reaction to the local anesthesia. Another rare consequence is the risk of preterm birth in some pregnancies. However, the likelihood of these complications is quite small—especially in experienced hands.

If I have a LEEP Procedure how often will I need to be followed? Your doctor will request frequent check ups and pap tests following this procedure. This may be as often as every 3 months during the first postoperative year.


                          GARDASIL THE NEW HPV VACCINE
          ADVICE TO WOMEN, PARENTS AND THEIR CHILDREN*


Should I get the new Gardasil (Quadrivalent Human Papillomavirus Types 6, 11, 16 and 18) Recombinant Vaccine?




Merck's new HPV vaccine, Gardasil, protects against 4 types of the human papillomavirus. But before you receive this vaccine or advocate its use for your child it's worth your while to learn some cervical cancer and genital wart "basics" and put this disease in its proper perspective as a threat to you or your children's health.

Invasive cervix cancer is a terrible and fortunately rare disease. Genital warts, while unseemly and embarrassing are, in fact, among the more "benign" STDs—unfortunately, there are worse diseases out there! The vaccine protects against two of the more than dozen viruses that cause warts. This discussion, however, will focus on the vaccine and its protection against invasive cervical cancer.

Since the 1954 invention of the Pap smear by Dr. George Papanicolaou, invasive cervical cancer, once the leading cause of cancer deaths in women, is now a rare disease1 according to the National Cancer Institute. The NICI reported thirty-seven hundred deaths from cervical cancer in 2006. . That same year 79,560 women died of lung cancer, 56,660 of colon cancer, 40,410 of breast cancer and over 16,000 women died of each of the following 3 cancers—rectal, ovarian and pancreatic. Uterine cancer claimed 7,310 women while cervical cancer was 14th on the list

Unfortunately, the aggressive marketing of the new Gardasil vaccine would have you believe that many women are dying of this disease. Consider that during 2006 almost 600,000 women died of strokes and heart attacks. In other words for every woman that died of cervical cancer 160 died of heart disease and strokes. But because the only "cures" for heart attacks and strokes involve lifestyle changes, no one advertises very much about these very real threats to a woman's health. As a result of this unbalanced marketing of real health threats we have an enormously misguided perception that women everywhere are at risk of a cervical cancer fatality.

Invasive cervical cancer typically follows a succession of stages that starts with abnormalities detected on Pap smear. These pre-cancerous changes, called dysplasias, are caused by HPV types 16, 18 as well as over a dozen others. Gardasil protects against types 16 and 18—which are responsible for an estimated 70% of cervical dysplasias. The other protection provided by Gardasil is against genital warts (types 6 and 11) which is a self limiting and an easily treated infection. The cause for excitement among the medical and pharmaceutical industry is, however, that this vaccine may provide protection against invasive cervical cancer.

It takes about 10 years for a cervical dysplasia to progress to invasive cervical cancer. The average age of American women with invasive cervical cancer is 50-55 and the vast majority of them are poor and didn't get regular Pap smear screening. Additionally, most cases of cervical cancer are associated with lifestyle choices—early onset of sexual activity, multiple partners, partners with multiple partners, cigarette smoking and obesity.
If you're really concerned about cervical cancer consider, what Gardasil doesn't protect against--HIV, hepatitis, syphilis, herpes, gonorrhea, Chlamydia, bacterial vaginosis, pelvic inflammatory disease, many other forms of venereal warts and a host of other viruses that also cause cervical cancer. And Gardasil doesn't protect against an unplanned pregnancy. Indeed what this vaccine may offer is possibly a very false sense of security.

If you're thinking about Gardasil for your self please understand that's effect on your overall health is probably minimal at best and unknown at worst.

If you're a mother or father wondering whether your pre-teen or adolescent daughter should get the vaccine I don't have any clear answers for you. I can tell you what I, as the father of 3 daughters, what I would have advised them if they were young adolescents. 

    First. I would strongly impress on my children the consequences of dangerous lifestyle choices-- sexual irresponsibility, multiple partners, early onset of sexual activity and cigarette smoking --not only a risk factor for cervical cancer but, worse, lung cancer, heart disease and strokes. According to a recently published Swedish study—one of the largest to date on the subject-- women who smoke cigarettes and who are infected with high levels of human papillomavirus type 16 (HPV-16) increase their risk of cervical cancer as much as 27-fold (2700%!). The researchers2 found that women who are positive for HPV-16 on their first smear and who smoke are "only" six times more likely to develop the disease than an HPV-16-positive nonsmoker. Not smoking makes a big difference! 

    Second. I would instill the habit of seeing a woman's health care provider at an appropriate time. For young women who are not sexually active and are not having any problems they should get their first internal exam and Pap smear at age 21. Young women who are sexually active should seek professional advice regarding sexually transmitted diseases and contraception. The US Preventive Services Task Force (USPSF) and the American Cancer Society (ACS) recommends that a first pap smear be performed within 3 years of the onset of sexual activity. 

    Third. I would remind myself and my children that sexual activity is far from the only hazard of being an adolescent. Adolescents are the only segment of the U.S. population with a rising mortality rate --11% in the last 20 years! Tragically, teen-agers today are as likely to die before reaching their 20th birthday as they were in the 1940s and 1950s. What are they dying of? The number one cause of death from the age of 1 through 21, by far, is accidents. Homicides are the next most common cause of death followed by suicides. Accidents, homicides and suicides are responsible for 77% of deaths in the age group between 15 and 24! Know your kids. Discuss motor vehicle safety, the hazards of driving with reckless friends, the risks of speeding, alcohol, cocaine, ecstasy, heroin, methamphetamine and other illicit drugs. Know who their friends are and whether or not your children are undergoing a significant personality change.

So if you're a concerned parent don't stop being concerned—be vigilant. But keep it in perspective. As responsible parents we want to be in control of our children's health. We want to protect them against all the tragedies of the real world. This vaccine gives us some sense of being in control. The problem is that if you put cervical cancer into perspective and begin to understand the real risks of adolescence and early adulthood you quickly realize that the vaccine is a very small corridor in a very large maze that our children must negotiate safely—a maze that we ultimately have very little control over once they leave our homes.

If you're considering Gardasil for yourself this is a good opportunity for you to ask yourself if your own lifestyle needs adjustment. If you have a responsible approach to sex and driving, avoid illegal drugs, alcohol and don't smoke or abuse alcohol and get regular annual exams by a woman's health care professional you have already done a great deal more for yourself than the HPV vaccine ever could—and then some.

Gardasil costs about five hundred dollars—the cost of the 3 vaccinations and the office visits for its administration. You should really ask yourself if you would spend that amount of money if the vaccine wasn't covered by your insurance carrier. That's a lot of money for an unproven vaccine against a cancer for which we already have an excellent screening tool. We do not yet know the risks of this vaccine in a large study population over a period of 20 years. Let me also emphasize that the long term efficacy in reducing invasive cervical cancer is yet unproven. All that Gardasil is known to prevent is "pre-cancerous" conditions such as dysplasia or carcinoma in situ (which is not invasive cervix cancer and is virtually 100% curable).
We don't yet know whether a booster will be required much less how often.

In time we'll know the value of this vaccine. While we're waiting for answers there are things you, as a woman, can do for yourself and your children now. Be responsible about your sexual activity and teach the same behavior to your children. If you're a smoker quit! Children are much more likely to smoke if one of their parents is a smoker. Make regular visits to a women's health care provider or a family doctor who is comfortable with providing those services. Teach your daughters to do the same.

Many one-time "wonder drugs" produced unintended consequences or simply didn't live up to their marketing hype—hormone replacement therapy, Fen-phen, Celebrex and Vioxx are just a few examples.

Lastly, if you're going to take advice from someone (or a televised commercial) take it from a knowledgeable individual
who doesn't stand to profit from that advice. 

  1. www.rarediseases.info.nih.gov/html/reports/fy1999/nci.html 
  2. Gunnell AS, Tran TN et al. Synergy between cigarette smoking and human papillomavirus type 16 in cervical cancer in situ development. Cancer Epidemiol Biomarker Prev. 2006;15:2141-2147

*This article expresses the sole opinion of Dr. Morris Wortman. Any individual who is considering the vaccine should make an informed decision with their health care provider.

Contraception


Obesity


Two–thirds of American adults are overweight with one out of three considered obese. We are now witnessing a health care epidemic. Between 1976–1980 and 2003–2004, the prevalence of obesity among adults aged 20–74 years increased from 15.0% to 32.9%. The problem cannot be overstated. In my opinion we will soon witness the first decrease in life expectancy in the United States since 1900. If current trends are not reversed we can expect to see an increase in early deaths due to diabetes, hypertension, heart disease and strokes. Presently 300,000 deaths per year are linked to obesity.

Obesity is generally defined as having a body mass index (HMI) of 30 or greater. One is considered overweight with a BMI or 25-30.

Weight is largely determined by the balance we strike between the calories we take in from food and the energy we expend during our daily activities. If we take in more calories than we use the unused calories get stored as fat.

What are the risk factors?

·Diet. The regular consumption of foods that are calorie-rich, frequently found in fast foods, fatty foods, soft drinks, candies, deserts are the general culprits. The average American skips breakfast and often eats the bulk of their calories late in the afternoon and evening. This provides a cycle of fasting and binging which is another problem with the average American's lifestyle.

·Inactivity and lack of exercise. Sedentary people are more likely to gain weight because they don't burn calories through physical activities.

·Psychological factors. A lot of women don't realize that they eat when they're not actually hungry. Many women overeat to cope with daily stresses or to deal with difficult emotions. Some women eat out of boredom.

·Genetics. If one or both of your parents are obese, your chance of being overweight is greater. Your genes may affect your chances of becoming obese and even where fat is distributed. But a family history of obesity does not mean that you have no ability to control your weight.

·Age. The older we get the less active we become. Muscle mass also declines with age (especially without exercise). Since muscle mass is related to calorie consumption, the loss of muscle mass also slows down our metabolism and increases our chances of gaining weight. Again, this doesn't mean that we're helpless. It does mean that in order to prevent weight gain we have to take a disciplined approach to exercise.

·Cigarette smoking. Many women smoke in order to control their food cravings and maintain their weight. When you quit smoking you're at greater risk for gain weight. Why? Nicotine, apart from suppressing your appetite, increases your metabolic rate. With smoking cessation (unfortunately) your appetite may increase along with your slowing metabolic rate. The net result is that when smokers stop, they burn fewer calories and often gain weight. However, cigarette smoking is still considered a greater threat to your health than the extra weight.

·Pregnancy. During pregnancy a woman's weight should and does increase. Some women find this weight difficult to lose after the baby is born. This weight gain may contribute to the development of obesity in women.

·Medications. Corticosteroids and tricyclic antidepressants, in particular, can lead to weight gain. So can some high blood pressure and antipsychotic medications. Depo-Provera has been associated with some weight gain. Birth control pills, on the other hand, are not associated with significant weight gain. While this may have been true of oral contraceptives in the 1960s and 70s this argument doesn't pertain to today's very low dose pills, contraceptive patches and rings.

·Medical problems. Uncommonly, obesity can be traced to a medical cause, such as low thyroid function, excess production of hormones by the adrenal glands (Cushing's syndrome) or other hormonal imbalances, such as polycystic ovary syndrome. A low metabolic rate is rarely a cause of obesity. A medical problem, such as arthritis, can also lead to decreased activity, which can result in weight gain.

·Alcohol. Many women are surprised to learn that just one regular beer contains about 150 calories. Many people are unaware that the calories in 2 glasses of wine taken every day can add up to some serious weight gain over the course of time. Additionally, excessive drinking can stimulate your appetite and make you less likely to control portion sizes.

When should I seek medical advice?

·BMI (Body Mass Index)

Unfortunately, few women actually seek medical advice regarding their weight and most have no idea what their BMI is. If you wish to make a quick calculation visit this link:

http://www.cdc.gov/nccdphp/dnpa/bmi/adult_BMI/english_bmi_calculator/bmi_calculator.htm

The BMI is not a perfect tool. It doesn't make allowances for women with a high muscle mass—unfortunately unless you're a weight lifter this probably doesn't apply to you.

If you're BMI is between 19 and 24 you're considered in a healthy weight range for your height. At a BMI between 25 and 29 you're considered overweight and with a BMI of 30 or greater you're considered obese. If you're in the latter two categories it's a least worthwhile getting some advice.

·Waist Circumference

Weight distribution varies from one person to the next. Some women carry most of their weight around their hips, thighs and lower body and are "pear shaped". Others carry most of their weight in their upper body and waist and are "apple shaped". When it comes to your overall health it's better to be "pear shaped". Women with a waist over 35 inches have an increased incidence of various serious diseases including hypertension, diabetes, heart disease and the metabolic syndrome. So if you're apple shaped with a BMI over 25 you now

·Weight-related medical condition

A BMI over 25 increases your risk for hypertension, hypercholesterolemia, diabetes and arthritis. These conditions often improve (and even disappear) with weight loss.

·Life-style issues

If you smoke, drink excessively and have a sedentary lifestyle coupled with a great deal of personal stress take action sooner rather than later. This is not a problem that gets better by itself.

Think about this

There are no magic pills or quick fixes to accomplish weight loss. Obesity, whether mild, moderate or severe is a national epidemic. Changing your weight is one of the most challenging things you can do and requires a tremendous commitment to an ongoing lifestyle change. Your weight is an important factor that will affect your risk of heart disease, strokes, diabetes, arthritis, sleep apnea, gall bladder disease, "fatty liver", gout and even cancers (breast, colon and uterine).

The good news is that even modest weight loss can fix a world of ills—lower your blood pressure, lower your cholesterol, improve your diabetes, sleep apnea and arthritis. It can even lower your risk for developing some cancers. For many people the loss of 10 lbs is the difference between taking blood pressure medications or statins for their hypercholesterolemia. The best weight loss happens, not with crash diets that are not sustainable, but with slow and steady lifestyle and dietary changes. Exercising is an invaluable part of a weight loss regime. Don't even start by saying you don't have the time. Make an appointment with yourself at least 4 times a week for an hour and exercise.

Getting started on a weight loss program

There are many ways to successfully lose weight and there are many ways to fail. The best way to get started, in most cases, is to get some help. Start with your health care provider to put this issue in its proper perspective. Some women who think they have a weight problem don't. Still others are quite naïve about the degree of the problem they do have and how it's affecting their overall quality (and quantity) of life. If you've tried losing weight on your own and have not succeeded call and schedule an appointment. We can get you pointed in the right direction. You might be interested in some of these websites:

http://www.consumer.gov/weightloss/setgoals.htm
http://www.cnn.com/HEALTH/library/HQ/01625.html

http://exercise.about.com/cs/weightloss/a/weightsuccess.htm


 Smoking Cessation



Smoking increases your risk for heart disease, strokes, chronic obstructive pulmonary disease (emphysema or COPD), lung cancer, cataracts, macular degeneration (which causes blindness), Graves disease, thyroid cancer, cancers of the lips, mouth, throat and larynx (voice box). Smokers also have an increased risk of other cancers including esophageal, stomach, kidney, bladder, skin and pancreatic cancer. Apart from cancer smoking causes premature aging of the skin and increases your risk for peptic ulcer disease.

According to the CDC between the years 1997-2001 "The three leading specific causes of smoking-attributable death were lung cancer (123,836), chronic obstructive pulmonary disease (COPD) (90,582), and ischemic heart disease (86,801)."

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5425a1.htm

There are many, many other reasons to quit if you're a woman. Smoking has potentially devastating effects on fetal well-being for women who smoke during pregnancy. Smoking increases the likelihood of stillbirths, low birth weight infants, premature births and even sudden infant death syndrome (SIDS). Smoking is associated with an increased risk of cervical cancer, osteoporosis and urinary stress incontinence.

Smoking is deadly and is responsible for the deaths of nearly 430,000 people a year--more lethal than AIDS, automobile accidents, homicides, suicides, drug overdoses and fires combined!

Smoking diminishes the quantity and quality of life. On average, female smokers reduce their life from by 14.5 years! Apart from that, smoking also decreases the quality of life and is associated with many disabilities.

The smoke contained in cigarettes contains tar along with many other inhaled chemicals. Some of the chemicals are known carcinogens—cyanide, benzene, formaldehyde, methanol, ammonia and acetylene.

No wonder the U.S. Surgeon General has stated" Smoking cessation represents the single most important step that smokers can take to enhance the length and quality of their lives."

No matter how old you are right now you can improve your life expectancy by quitting. Quitting before the age of 50 reduces by half your risk of dying in the next 15 years. Former smokers also have a reduced rate of bronchitis and pneumonia.

Why is quitting so tough?

The answer is nicotine. Nicotine is a drug naturally found in tobacco. It is highly addictive. Arguably, nicotine is more addictive than heroin and cocaine. Nicotine causes a real psychological and physical dependence in exchange for a temporary pleasant and calming sensation for most smokers. As the nervous system adapts to nicotine, smokers tend to increase the number of cigarettes they smoke in order to overcome to the tolerance they develop.

When smokers try to cut back or quit, the absence of nicotine leads to withdrawal symptoms. These include dizziness, depression, frustration, anger, irritability, sleeplessness, headaches, restlessness, fatigue, an increased appetite. No wonder Mark Twain once said "quitting smoking is easy. I've done it a thousand times."

Why should I quit?

The simple answer is "your health". The Centers for Disease Control (CDC) estimated that the average female smoker loses 14.5 years of life!

Smoking is related to a long list of cancers (see above), progressive non-cancerous lung diseases (chronic obstructive pulmonary disease) and other diseases that dramatically shorten life expectancy. In all age groups smokers are twice as likely to die of a heart attack as non-smokers. Smoking also dramatically increases the risk of strokes and peripheral vascular disease. Just as smoking narrows medium and small blood vessels it also causes narrowing of the large blood vessels to the arms and legs.

There are plenty of other reasons to quit too. There many workplace restrictions today on smoking. Some employers may not hire you if you're a smoker. Public buildings, hospitals, concerts and sporting events all have restrictions on smoking. New York State doesn't allow smoking in restaurants and bars. In the last 10 years smoking has gone from being socially acceptable to unacceptable. With evidence mounting against second-hand smoke you also have the health of others to consider—especially if those "others" are your children or loved ones. If you have children you need to think about setting a good example for them too. And if that isn't enough consider this—you'll pay twice as much for life insurance if you're a smoker.

Lastly, many work places from large corporations to small businesses are beginning to require not only smoke free environments on the job but that you lead a healthy lifestyle. Some businesses go so far as "drug testing" to see if you are "smoke-free". This issue is still working its way through the court system to determine whether or not it's legal for businesses to do so. In the meantime, business have fired smokers and refused to hire them.

Common reasons for not quitting

· It's stressful—this may "lead the pack" in realistic reasons that women don't want to quit. Nicotine does cause psychological and physical dependence.

· I'll gain weight—no question this happens in most cases. In every case the cigarettes are worse for you health than the weight gain. Deal with one problem at a time. Expect to gain some weight and then make sure that your next lifestyle change you will address are the issues of diet and exercise.

· I worry about the side effects of medications—not all women who quit require medications. But even if you're taking medications remember that whatever side effects they may have (a) you're not going to taking them for the rest of your life and (b) they are far less risky to your health than cigarettes!

· I can't afford the medications—that's ridiculous! Consider that a pack of cigarettes are now costing 5-7 dollars a pack. If you're smoking a pack a day that's $1800 – 2500 dollars per year! You can pay for your medications and still have a lot of money left over. Landlords may not rent to you and friends may not allow you to smoke in their homes. Public buildings, hospitals,

· Now is not a good time—perhaps you're right about this one. If you're in the midst of a divorce, a legal action, mourning over the loss of a loved one or dealing with an acutely sick family member or job loss it might be best to put this decision off for a few weeks or even a few months. But don't use this as a chronic excuse. In most cases there's never a better time than right now.

How do I get started?

There is no one right way to quit. Success has come from "going cold turkey", acupuncture, hypnosis, nicotine replacement (lozenges, patches, gum), bupropion (Zyban or Wellbutrin) and verenicline (Chantix). And all of these methods have failed.

The key elements of successfully quitting involve four crucial steps:

  • Make a decision to quit
  • Set a quit date, and choose a quit plan
  • Manage withdrawal
  • Maintain success

Learn more about ways to quit by visiting the American Cancer Society's "Kick the Habit" web page:

http://www.cancer.org/docroot/PED/ped_10_3.asp

Generally speaking smoking cessation requires a combination of approaches—behavioral and often medical. There is no single and simple approach for most people.

The American Cancer Society web-link above is a great resource. Additionally,

New York State has a great many resources available to its residents through the following link:

http://www.nysmokefree.com/newweb/default.aspx

If you need help here are some resources available in Monroe County

American Lung Association                 1595 Elmwood Avenue                   585-442-4260
                                                                 Rochester NY 14620

Greater Rochester Area                       220 Alexander St. Suite 409            585-530-2050

Tobacco Treatment Center                      Rochester NY 14607

NYS Smokers' Quitline                               1-866-NY-QUITS                         1-866-697-8487

Medications you should be aware of

We are not advocating the use of medications as a "one size fits all approach". However, many women have found medications very helpful for them while others experience no relief from nicotine withdrawal whatsoever. As of this writing Chantix has recently been approved by the FDA and we are just now getting more experience with this particular medication.

Some commonly used medications are:

Nicotine replacement therapy (NRT)—The AHA (American Heart Association) believes that nicotine replacement in the form of patches, lozenges, spray, inhaler and gum can help smokers quit as part of a comprehensive approach to smoking cessation. NRT almost doubles the chances of someone being able to successfully quit smoking. As already noted nicotine is a very addictive substance whose withdrawal leads to irritability, depression, food cravings and headaches. Learning the skills to quit smoking while dealing with nicotine withdrawal just makes it harder to successfully quit.

If you're planning on using NRT it's best to select a "quit time" for smoking cessation and plan the use nicotine replacement immediately. Remember that symptoms of nicotine withdrawal start in hours after smoking cessation. If you are using NRT use it consistently in the beginning and not just "every now and then". Some experts even advocate a combination approach to NRT such as using a patch as a form of baseline suppression along with lozenges, gum or spray when cravings become more acute.

If you're pregnant or have heart disease you should have a thorough discussion with your health care provider before using NRT.

What about smoking while taking NRT? It's not unusual, in the early stages of cessation for someone to smoke a few cigarettes while using a nicotine patch or other forms of NRT. If you're smoking only 2-3 cigarettes per day it's okay to use the NRT with the understanding that your goal is stop smoking completely in a short period of time. However, if you find yourself smoking as much as you did before attempting to quit you should stop taking NRT and consult your health care provider.

Bupropion (Wellbutrin, Zyban)

Buproprion has a long history as a very useful adjuvant to smoking cessation. It can be used with nicotine replacement therapy and is generally very well tolerated provided that one starts it at a very small dose. Some women are very sensitive to this medication's temporary side effects which include rapid heart rate, jitteriness, anxiety, headache, insomnia, nausea and dizziness. If you find that you're experiencing severe side effects stop the medication but ask to be re-started at half the dose. These side effects may last 2-4 days but improve quickly thereafter. Generally, this medication is started at 150 mg and increased to 300 mg per day after a week. Some women require only a minimal dose to appreciate profound improvement in the withdrawal cravings. It is recommended that you avoid excess alcohol with this medication especially if you have alcoholism or severe depressed. Ask your health care provider, however, about alcohol use while taking Bupropion.

Bupropion is an anti-depressant in a category of medications known as dopamine-reuptake inhibitors. These medications are not sedating and do not have the sexual side effects in selective serotonin reuptake inhibitors (SSRIs). Some women are able to take bupropion for a few months and then taper themselves off the medication. Other women require bupropion for long periods of time in order to stay smoke free. Just remember that the long term use of bupropion is safe—that's not true of cigarettes.

If you are taking bupropion you can minimize any sleep disturbance by taking it first thing in the morning.

Varenicline (Chantix)

Chantix was introduced by Pfizer in May of 2006 and is currently a less well known drug. As with any new drug its true effectiveness over a long period of time has not been studied on large populations. It has two mechanisms of action. First it mimics the effects of nicotine on the brain and helps stave off nicotine cravings. When used with nicotine it blocks some of the pleasurable effects of smoking. In clinical trials the main side effect was nausea (40%). Other significant side effects are insomnia (18-19%), headaches (15-19%) and abnormal dreams (9-13%). Many of the side effects can be reduced by starting at a low dose and gradually increasing the medication to a maintenance dose.

For the first week Chantix is taken at the dose of 0.5 mg per day for 3 days, followed by 0.5 mg twice a day for the next 4 days. That completes the first week on Chantix. Thereafter Chantix is taken at the dose of 1.0 mg twice daily for another 11 weeks. The total treatment program is 12 weeks though it has been approved for longer use in patients who have successfully quit.



Sexually Transmitted Diseases (STDs)


Introduction

The Reality of Sexually Transmitted Diseases (STDs)

Viral infections
    
Human Papillomavirus (HPV)
    
Genital herpes virus (HSV)
    
Hepatitis B Virus (HBV)
    
HIV/AIDS

Bacterial infection
    
Pelvic inflammatory disease
    Chlamydia
    Gonorrhea
    Syphilis
    Bacterial Vaginosis

Parasites
    
Trichomonas vaginitis

Rare infections
    
LGV (lymphogranuloma venereum)
    
Chancroid


 

Introduction

There are many reliable websites available to obtain information about sexually transmitted diseases. My hope is not to replicate them but to distill them, to provide you with some valuable information and to address some issues that you may not find in your internet or library searches.

It is rare to find a sexually active individual who has not had an STD. What? How can that be? STDs are common, most existing in an asymptomatic form. Most of the STDs I'm referring to have never been a problem and never will be a problem for those that have them. Other sexually transmitted diseases, however, can have devastating consequences to one's health. In addition to the threat to a woman's health, an STD may have enormous consequences to her emotional well-being and self-esteem. A woman's initial reaction to the news that she has a sexually transmitted disease includes:

  • Depression
  • Despair
  • Betrayal
  • Loss of self-esteem
  • Anger

This is quickly followed by numerous questions that include:

  • How did I get this?
  • Can I give it to someone else?
  • How long have I had it?
  • Did he cheat on me?
  • Who did I get this from?
  • Can I pass it on to someone else?
  • Will I be able to have children?
  • Do I have to let my partner know?
  • Will I always have this problem?
  • Does this make me "dirty"?
  • How can I live with myself?

The Reality of Sexual Transmitted Diseases(STDs) is the Following:

Reality # 1: They are common!

STDs are common--especially among young people. The Alan Guttmacher Institute (AGI) analyzed and published an important survey in January of 2004 [Perspectives on Sexual and Reproductive Health, 2004, 36(1):6-10]. In their study they note the following:

  • 18.9 Million new cases of STDs were reported in the year 2000
  • 15-24 year-olds represent 25% of the sexually experienced population
  • 9.1 Million of the newly diagnosed STDs reported in 2000 were among 15-24 year-olds
  • 3 STDs (human papillomavirus, trichomoniasis and chlamydia) accounted for 88% of all new cases of STD among 15-24-year-olds.

Additionally, consider some additional information:

  • In March 2007 the National Cancer Institute reported that the overall prevalence of HPV in the U.S. in women ages 14-59 was 26.8%
  • At any one time there are 20-40 million Americans with HPV
  • About 60 million Americans have had the virus that causes genital herpes
  • As estimated 3 million Americans are infected with chlamydia each year
  • In 2005 there were 339,593 cases of gonorrhea reported in the United States.
  • About 10,000 women are diagnosed with HIV each year in this country—80% of these cases arise from heterosexual contact.
  • Each year in the U.S. more than 1 million women experience an episode of acute pelvic inflammatory disease (PID)--more than 100,000 women become infertile as a result.

Reality #2: Not all STDs cause symptoms

Many STDs cause symptoms such as foul odor, vaginal discharge, redness, soreness, warts and other visible lesions. The majority of STDs, however, cause no symptoms at all but exist in an asymptomatic or dormant state—at least for a while. It is this asymptomatic state that allows an individual to unknowingly pass it on and cause a serious infection to his or her partner. Examples include HPV, genital herpes, hepatitis B, chlamydia, gonorrhea and HIV.

Reality #3: STDs cover a broad spectrum of diseases.

Some of these diseases are not serious and do not generally have a large emotional component for most women (examples include bacterial vaginosis and trichomoniasis).

At the other end of the spectrum are diseases that can be life-threatening such as HIV/AIDs and viral hepatitis.

There are diseases which are not life threatening but can pose a significant threat to one's future fertility—gonorrhea, chlamydia, and pelvic inflammatory disease (PID).

There are diseases which are not life threatening and generally do not pose a significant threat to future health but are not completely curable either. Examples of such STDs are human papillomavirus (HPV) and genital herpes. The emotional reaction most women have to HPV is quite variable and to some extent depends on how the disease manifests itself—warts or abnormal pap smears.

Still there are other diseases that are serious but easily eradicated such as syphilis.

There are sexually transmitted diseases that carry a tremendous emotional stigma well out of proportion to the actual damage caused by the disease—genital herpes is perhaps the perfect example of an STD that often causes an emotional breakdown well beyond what can be justified by its implications for potential harm.

Finally, there are rare diseases that you've never even heard of but should be aware of such as lymphogranuloma venereum (LGV) and chancroid.

Reality #4: The risk factors of STDs are well known. They include:

  • Young age (15 to 24 years old)
  • African-American race
  • Unmarried status
  • Geographical residence
  • New sex partner in past 60 days
  • Multiple sexual partners
  • History of a prior STD
  • Illicit drug use
  • Admission to correctional facility or juvenile detention center
  • Meeting partners on the internet

Reality # 5: There's lots of misinformation out there!

For over 30 years I've talked to professional women who believed that herpes increased their cancer risk, that HPV would make them sterile and that HIV wasn't as serious a problem as it "used to be". Many of these women claimed to get their information from the internet, their friends, television commercials, their parents, magazines and even another health care provider. Some women admit that their beliefs aren't based on any known facts, but instead harbor beliefs based largely on their own fears. I'm constantly amazed by the apparent willingness of ignorant, unqualified and "well meaning" individuals to offer their "help". Still more surprising is that many women accept the information they get from unqualified individuals or from dubious sources (women's magazines, paid advertising by pharmaceutical companies). Few things are as dangerous in the medical world as the intersection of good intentions, ignorance and panic.

Perhaps the only thing worse than no information is too much information! In order to obtain sound advice be certain of two things—that your information source is qualified and that they have no financial interest in the information they dispense.

So be careful of your information source! This includes your best friend, a neighbor who happens to be a nurse, your mother, boyfriend, most newspaper and magazine articles and many websites.

Also be skeptical of individuals and corporations that stand to profit from the information they dispense—various websites and pharmaceutical companies that advertise heavily on TV and in magazines.

Oftentimes, government websites are some of the best sources of information available. Consider some of these.

Reality #6: In many cases, even knowledgeable health professionals don't have all the answers to your questions

In some instances it isn't possible to know the medical answer with certainty. For example, if you've had a positive chlamydia culture but not had symptoms it's unlikely that it will impact your future fertility but there is virtually no way to be certain about your ability to conceive in the future—at least not until you try. If you've been diagnosed with genital herpes should you take medication to prevent possible recurrence or to decrease the likelihood of infecting your partner? The answer will depend on many factors, but ultimately involves some "guesswork" on the part of your health care provider as well as your own comfort level. Your health care provider will not be able to provide you with exact statistics on the likelihood that you'll suffer a recurrent infection or the likelihood of infecting your partner.

Reality #7: Even when medical information is available the decisions you make may depend on personal psychological factors.

For instance, it may not make much "medical sense" for someone who had a mild case of genital herpes to take prophylactic anti-viral medication for the rest of their life. Yet, rarely, some women insist on doing so. For them, the psychological benefit of feeling that they are actively preventing even a small risk of recurrence or transmission is worth the cost and burden of taking daily medications for extended periods of time.

Reality #8: In many cases there is no "one size fits all" answer.

If you had venereal warts 10 years ago and have not had a recurrence since, is it necessary to tell your partner? The answer to this question will depend on many circumstances and there is no "one size fits all" answer.

Reality #9: Asking your health care provider to "test me for all STDs" is often not realistic—worry about the ones that are important to you.

Health care providers generally test for serious STDs that can affect your health. For instance we encourage testing for HIV, hepatitis, gonorrhea and chlamydia. Whether or not routinely screen for syphilis, herpes and HPV is a more complex issue and depends somewhat on your medical history, your symptoms and lifestyle. Routine testing to determine if you've even been exposed to oral or genital herpes may or may not provide helpful information to you. The same may be true of routine HPV screening for women with negative pap smears and no physical findings. The extent to which you require testing will depend on your risk factors (see above), your understanding of these diseases and your need for reassurance. Ironically, women who seem most concerned about STDs are often at lowest risk while woman at very high risk for STDs frequently avoid testing altogether. Another irony is that women often wish to be tested for comparatively benign diseases such as bacterial vaginosis or herpes while refusing HIV or hepatitis screening.

Reality #10: Medications alone cannot heal the psychological trauma

I'm often stunned to hear the following from women: "I'd rather have cancer than herpes". What an incredible statement! Genital herpes is an STD that in the vast majority of cases causes little pain, few recurrences, does not affect future fertility and does not cause cancer. The real implication of herpes is its "stigma". So powerful is that six-letter word that it has driven some women to thoughts of suicide and even homicide--the assumption being that their husband or boyfriend "gave" it to them. But the fear and stigma associated with the word "herpes" often blocks out rational thought to such an extent that conversation isn't even possible until the crying, the anxiety and the hurt begin to subside.

Reality #11: STDs are the result of lifestyle choices

It comes as no surprise that STDs are more prevalent in younger age groups (15-24). Youth is a time of growth, experimentation and often poor choices. Many errors—some serious—result from testing the limits of vehicular speed, alcohol, drugs, sex and emotional fulfillment. No one passes through life without making some bad judgments, but a wise person learns to minimize risks, learn from mistakes and commit to self improvement. Making mistakes is human foible— to not learn from them is a human tragedy. Multiple partners multiply your risk. Condoms offer some, but only limited protection. The best protection against STDs is a mutually monogamous long term sexual relationship with a trustworthy partner.

Putting STDs in perspective

Once a woman has entered the arena of sexual expression the risks of sexually transmitted infections become real. Those who are too frightened to assume even the slightest risk of a sexually acquired infection may avoid contact altogether. Those who are careless, reckless and thoughtless expose them selves and their partners to emotional and physical pain. Most men and women live in the midst of this spectrum—desirous of an intimate relationship and intelligent enough to avoid needless risk. Arm yourself with as much knowledge as possible, practice a disciplined approach to sexuality and be thoughtful to your partner. Life is fraught with risks but a wise person learns to manage them.


Human Papillomavirus(HPV)



Human papillomavirus (HPV) is the most common sexually transmitted disease in the United States. With more than 6 million new cases reported each year it occurs more frequently than trichomoniasis, chlamydia, gonorrhea, syphilis, genital herpes, HIV and hepatitis B combined!



The major implications of this virus for women are two-fold: first, it can cause venereal warts and second it has the capacity to cause cellular changes of the cervix that can lead to Pap smear abnormalities (usually transient and reversible) and, in rare instances, this virus can cause cervical cancer. Despite well-funded advertising campaigns that would have you believe otherwise, HPV is common while invasive cervical cancer is classified by the National Cancer Institute (NCI) as a rare disease.

It is estimated that at any one time there are 20-40 million cases of HPV infections in the U.S. (prevalence) and that over 6 million new cases occur annually (incidence). It is estimated that 75-80% of sexually active adults will acquire a genital tract HPV infection before the age of 50. The prevalence of cervical HPV infection decreases sharply in women after the age of 30. Those with persistent infection are at the highest risk for the development of high-grade precancerous lesions or invasive cervical cancer.

Human papillomaviruses are a group of viruses called "double-stranded DNA viruses". There are over 100 types of human papillomaviruses (HPV) that can divided into two groups—those that infect the skin (such as plantar warts) and those that infect mucous membranes (such as the tissues in the vagina, vulva, the cervix and the tissue around the anus. Flat warts of the skin are most often caused by HPV types 3 and 10. Plantar warts, very common in children and adults, are most often associated with HPV types 1, 2 and 4. HPV types 16 and 18 are most commonly associated with pre-cancerous changes of the cervix. However, HPV types 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68 and 69 are also associated with these pre-malignant changes. Genital warts, also called, condylomata accuminata, are frequently caused by HPV types 6, 11, 42, 43 and 44.

How do women get genital HPV infections?

Genital HPV is passed by skin-to-skin and genital contact, primarily during vaginal and anal intercourse. However, actual vaginal or anal penetration isn't necessary to acquire this virus. Skin to skin contact with genital contact or "outercourse" can also transmit this disease. It might also be possible to pass it during oral sex—though this is probably rare in the absence of visible lesions.

How do I know if I have an HPV infection?

Most women who have HPV infections never know it! Pap tests are excellent tools for detecting HPV-related abnormalities (click here). Your health care provider may also send an HPV test along with your pap smear to see if you are carrying a high-risk viral type. Another way you might know if you have an HPV infection is the presence of genital warts. These warts can grow inside the vagina, on the vulva or around the anus.

Who gave me HPV?

It isn't always possible to answer this question. You may have acquired it from your current partner or from one of your past sexual partners.

Is my partner unfaithful?

Not necessarily! Your partner may have acquired HPV from a previous partner and unknowingly became an asymptomatic carrier (a carrier with lesions so small that he never noticed). In fact, you may have harbored the virus in an asymptomatic form and then developed an infection.

Is HPV forever?

About 90% of HPV infections are transient and clear within 3 years without a woman ever realizing that she had the virus. The younger the person is when she gets infected the more quickly it clears. Sixty to eighty percent of new HPV infections clear within 1 year. This is true of women who have skin or mucous membrane lesions as well as women with mild Pap smear abnormalities, such as mild dysplasia (click here). Approximately 90% of young women with mild dysplasia will spontaneously revert to normal within 1 year.

Do condoms protect against HPV?

The answer is "not completely" and perhaps not at all. Condoms do not cover the base of the penis, the scrotum, anus etc. The HPV virus is easily spread during foreplay without penile penetration. Condom use is only one "piece of the puzzle" in reducing the risk of STDs and not as important as lifestyle choices. Simply put, the greater your exposure to different sexual partners the greater your risk.

Should my partner use condoms?

Given the fact that HPV is very easily transmitted from one partner to the next it's important to understand that condoms are of limited usefulness and then only partially helpful, even if used consistently.

What about the new HPV vaccine?

In 2006 Merck released its new HPV vaccine. This is a "quadrivalent" vaccine, meaning that it offers protection against 4 different HPV types (6, 11, 16 and 18). Remember that there over 100 various types of HPV and, therefore, receiving this vaccine provides only partial protection against genital warts and pre-cancerous changes of the cervix. The vaccine is best administered in children before they become sexually active. Since the vaccine has only been available in the U.S. for a relatively short period of time it has yet to be determined what its long term effect will be on reducing pre-cancerous changes of the cervix, cervical cancer and genital warts. It's also unknown if the vaccine will require a "booster" 5 or more years later. And like any new drug that is released by the FDA it will take many years before it's long term effects can be determined. For additional information on the new quadrivalent HPV vaccine click here.

Is HPV related to promiscuity?

Not necessarily. HPV has a very high prevalence rate in the population. Simply stated—it's out there! HPV is the most common of all sexually-transmissible agents. Additionally, HPV has a much higher risk of transmission than herpes or HIV during a single sexual act.

When should I get my first Pap smear and how often should I get one?

The American Cancer Society recommends that you get your first pap smear at age 21 or within 3 years of becoming sexually active---whichever comes first. Since the Pap smear has been adopted over 50 years ago, this country has seen a sharp decline in the number of women suffering from invasive cancer of the cervix. Pap smears should be performed annually. Modern pap smears are both painless and accurate. The cells that are obtained can be tested to see if they are abnormal in appearance and even for the presence of cancer-causing viruses.

If my Pap smear is negative can I be assured that I don't have HPV?

No. You can have HPV and still have a negative Pap test. And remember than most HPV types do not cause Pap smear abnormalities.

How are genital warts treated?

Genital warts cover an entire spectrum from being virtually undetectable to large masses with multiple lesions. Most warts, fortunately, are small measuring only millimeters in size. Some can be treated at home with a prescription medication called Podofilox. This agent is applied by the patient on an every other day basis for about 3 weeks. Other methods can be used in an office setting and include Podophyllin and trichloracetic acid, which is a caustic agent commonly used in the treatment of small genital warts.

For larger warts or warts that cover a larger surface area surgery may be recommended. Warts are easily removed by a variety of methods including, simple excision, cryosurgery (freezing), electrosurgery and laser surgery.


Genital Herpes (HSV-2)


Herpes is not—in the vast majority of cases---a serious medical condition yet it almost always produces much more hysteria than the diagnosis of hepatitis, chlamydia or gonorrhea. I suspect the hysteria that surrounds this diagnosis is based on the following four issues:

  • Some words, by their very sound are powerful and "loaded". Words like "herpes", ovarian "cysts" and "breast" cancer are more powerful words than "chlamydia", "hypertension" and "colorectal" cancer. The facts, however, tell another story--herpes causes few problem for most women, chlamydia may cause permanent sterility; ovarian cysts are "normal" in 99% of cases while hypertension is a major risk factor for heart disease and strokes. Breast cancer is more common than colorectal cancer but not nearly as lethal.
  • Herpes is a "chronic" condition—you don't fully eliminate it from your body. The same is true, by the way of chickenpox (also in the family of herpes viruses) which rarely causes us to feel "dirty" and has no "stigma".
  • There was once a time when herpes was thought to be the cause of cervical cancer. That theory has long since been dispelled, but the "fear factor" has persisted.
  • The media continues to hype "herpes". There are many reasons for this not least of which is that media advertising is often paid for by pharmaceutical companies who stand to profit from evoking fear from a disease for which they can sell the "cure".

In summary, the word "herpes" evokes shame, fear and self-loathing out of all proportion to the reality of the diagnosis. The combination of this diagnosis with underlying guilt and anxiety often results in consequences far greater than the disease itself. That said, it's important to learn about the specifics of this sexually transmitted disease.

What are the different types of herpes viruses?

We generally hear of two types of herpes virus infection—HSV-1 (oral) and HSV-2 (genital). The majority of genital herpes is caused by HSV-2. However, an increasing number of genital lesions are also caused by HSV-1—likely from oral-genital sex

How common is genital herpes?

Up to 80% of Americans have oral herpes (HSV-1) at some time in their lives. Between 45 and 60 million Americans have HSV-2—the virus that causes genital herpes. It is estimated that up to a million people become infected each year with genital herpes. Women are more susceptible to genital herpes than men.

What are the risk factors for genital herpes?

The major risk factors for genital herpes include:

  • History of a prior STD
  • African American race
  • Three to five years of sexual experience
  • Female gender
  • History of a partner with oral ('cold") sores

What are the symptoms of genital herpes?

In all likelihood the majority of individuals with genital herpes have no symptoms whatsoever. However, blood tests can reveal a history of a past subclinical infection. In other cases the symptoms are so mild that they are easily overlooked.

At the other end of the spectrum individuals whose symptoms can be so severe and disabling that they require prompt medical care. Symptomatic cases generally begin with one or more blisters around the genital or rectum. The blisters become increasingly sore and filled with pus (pustules). After these pustules break they leave a tender sore (ulcer) that may take 7-21 days to heal.

The first episode of symptoms of a genital herpes infection is called the "primary" infection. The localized symptoms of the primary infection include:

  • A "tingling" sensation
  • Blisters (vesicles or pustules)
  • Open sores (ulcers)
  • Pain in the infected area
  • Itching
  • Burning when urine comes into contact with a sore
  • Inability to urinate if sores are in the area of the urethra

In addition to these symptoms, primary herpes is often accompanied by systemic symptoms that include:

  • Fever
  • Swelling of lymph nodes in the groin
  • Headaches
  • Achy flu-like symptoms

The "average" primary infection takes about 2-3 weeks to clear up.

Can genital herpes recur?

Yes. Symptoms of genital herpes can come and go but the virus stays in the nerve cells of your body even after all signs of the infection have disappeared. In many people, the virus becomes "active" from time to time creating a "recurrent" outbreak. Some women have an outbreak only once or twice in their lifetimes. Others have many outbreaks each year. In general, recurrent outbreaks tend to be less severe than the initial one. Over time women generally experience fewer and fewer recurrences. In some cases outbreaks appear to be precipitated by stress, other illness, excessive sun exposure or even the onset of menstrual flow.

About half of women with recurrent infections have prodromal symptoms before an eruption of visible lesions. These symptoms include mild tingling or shooting pains in the buttocks, legs and hips. The average recurrence lasts for about 10 days.

How do I know for sure if I have genital herpes?

Health care providers can often diagnose genital herpes by the classic appearance of visible sores. In other cases, especially when the appearance is atypical, viral cultures can offer conclusive evidence of an infection. Blood tests, which detect antibodies to HSV-1 or HSV-2, can help to detect herpes in people without symptoms.

Can genital herpes be treated?

While there is no cure for genital herpes it can certainly be treated. The virus will remain in the nerve cells of your body. However, certain drugs such as acyclovir, Valacyclovir (Valtrex) and famciclovir (Famvir) can shorten the duration of recurrent outbreak, decrease the frequency of outbreaks and often prevent them from occurring entirely. When used in conjunction with safe sex practices Valacyclovir can help to prevent you from passing the infection to someone else.

During outbreaks, you should:

  • Keep the infected area clean and dry
  • Try not to touch the sores
  • Wash your hands after contact with the sores
  • Avoid sexual contact from the time that symptoms are first notice (often "tingling" is the first symptom) until the sores have completely healed.

In addition to these anti-viral medications the use of painkillers and even local anesthetic ointments can be very helpful during an outbreak.

What about genital herpes and pregnancy? Is there a problem?

If the mother is having her first outbreak while she is pregnant she is more likely to pass the virus to her baby. In general, transmission to the baby happens only if the baby passes through the birth canal and is exposed to the virus. Women who have herpetic lesions or who experience a prodrome (the symptoms one experiences just prior to the appearance of lesions) generally undergo Cesarean section in order to avoid the possibility of transmitting the virus to the fetus. The overwhelming majority of women with a history of herpes infection do not transmit the virus to their babies.

What can be done to protect myself from contracting genital herpes?

Aside from abstinence there is no way to completely avoid the risks of a herpes infection. However, these risks can be minimized. Here are some suggestions:

  • Have sex in the framework of a long term mutually monogamous relationship.
  • When in doubt, use condoms.
  • Understand that most methods of contraception (birth control pills, Depo-Provera, Implanon, Diaphragms, Intrauterine Devices and sterilization procedures do not protect against most STDs.
  • If you have any questions about symptoms you are experiencing contact your health care provider.
  • Talk frankly with your prospective partner before you establish sexual contact.

Is it possible to spread genital herpes to someone else if I don't have an active infection?

Yes. Even after resolution of the primary genital herpes infection, intermittent viral shedding can occur in the absence of any visible lesion. This has been documented in both men and women and is called subclinical herpes virus shedding.

Where can I get additional information?

CDC Info, HHS
Phone: (800) CDC-INFO or (800) 232-4636

CDC National Prevention Information Network (NPIN), CDC, HHS
Phone: (800) 458-5231
Internet Address:
http://www.cdcnpin.org

National Center for HIV, STD and TB Prevention, CDC, HHS
Internet Address:
http://www.cdc.gov/std

National Institute of Allergy and Infectious Diseases
Phone: (301) 496-5717
Internet Address:
http://www.niaid.nih.gov/publications/stds.htm

American Social Health Association's National Herpes Resource Center and Hotline
Phone: (919) 361-8488
Internet Address:
http://www.ashastd.org/hrc/index.html


Hepatitis B Virus  (HBV)


Hepatitis is an inflammation of the liver, which over time can lead to cirrhosis (scar tissue within the liver), liver failure and even liver cancer. Although there are several different kinds of hepatitis, including A, B and C, it is hepatitis B that is most often associated with sexual transmission.

Hepatitis B virus (HBV) is a blood-borne and sexually transmitted virus that can be spread from exposure to blood or semen as well as other bodily fluids. In the United States, approximately 1.2 million persons have chronic hepatitis B and are sources for HBV transmission to others. Since the late 1980s the incidence of acute hepatitis B has declined steadily, especially among vaccinated children. In fact, between 1990 and 2002 the Center for Disease Control (CDC) reported a 67% decline in the incidence of acute hepatitis B. The most common risk factor for hepatitis B is multiple sex partners and I.V. drug use. About 50% of hepatitis B in the U.S. is sexually acquired.

What are the symptoms of Hepatitis B?

About 30% of individuals with hepatitis B don't have symptoms. The majority, however will exhibit one or more of the following: jaundice, fatigue, abdominal pain, loss of appetite, nausea and vomiting as well as joint pain.

Who is at risk?

The major risk factors include:

  • Women with multiple sex partners
  • Women with a diagnosis of a sexually transmitted disease
  • Women who have sex with bisexual men
  • Sexual contact with an infected person
  • Intravenous drug use
  • Sexual contact with an I.V. drug user
  • Health care and public safety workers
  • Hemodialysis patients

So Hepatitis B can be transmitted by sexual contact?

Yes. Sexual transmission is less likely if condoms are used. In long-term relationships, the partners of carriers should be tested and, if susceptible, vaccinated against hepatitis B.

How can Hepatitis B be prevented?

If you haven't received the hepatitis B vaccine you should consult with your health care provider. The vaccine is safe and effective. Here are other precautions.

  • Use latex condoms if you are not in a long term mutually monogamous sexual relationship.
  • Do not use intravenous drugs. Never share needles, syringes, etc.
  • Do not share razor blades or toothbrushes
  • If you are a health care provider use routine "universal precautions"

What happens after infection with hepatitis B?

There are three possible responses to a hepatitis B infection.

  • About 50-60% who are infected get rid of the virus without becoming ill and become immune (protected from further infection).
  • About 20% of those that get infected will become ill with full-blow jaundice, abdominal pain, weakness and lethargy—they get "acute hepatitis". They will eventually get rid of the virus and not become a carrier.
  • Another 20% will develop acute hepatitis and become chronic carriers of the virus.

Do people carrying a chronic infection become ill?

Chronic carriers do not get ill when they are infected or for many years after their initial infection. Most will probably never suffer from the effects of the virus. However, some chronically infected people do develop cirrhosis, a serious liver disease, as adults. Cirrhosis can lead to liver failure and is often the setting for liver cancer. Women are less likely to develop liver cancer than men.

How do I know if I might be chronically infected?

A simple blood test can tell. If you are chronically infected you will need to check your liver functions periodically and be referred to specialists who can help you manage and avoid many of the long term consequences of being chronically infected.

Where can I get additional information?

You may wish to consult these additional websites.

http://www.cdc.gov/ncidod/diseases/hepatitis/b/

http://www.hepb.org/

http://digestive.niddk.nih.gov/ddiseases/pubs/hepb_ez/


HIV/AIDS


The most pernicious of sexually-acquired infections is HIV/AIDS. Though there are different mechanisms for contracting this infection (see below) it is extremely important for women to understand that this is not a disease limited to gay men or I.V. drug users. Women now constitute the most rapidly growing segment of the HIV-infected population in the U.S.

HIV infections were first reported in 1981, although the disease was probably around for 20 years prior to that. According to the World Health Organization (WHO) the human immunodeficiency virus (HIV) has claimed more than 25 million people worldwide making it one of the worst pandemics in history. In 2005 alone AIDS claimed almost 3 million lives of which more than half a million were children. Only the Black Death or bubonic plague (1347-1351) and the Great Influenza Pandemic (1918-1919) claimed more lives. But unlike those terrible disasters the final chapter on HIV/AIDS has yet to be written. In 2006 over 39.5 million people were living with HIV/AIDS—an increase of 2.6 million since 2004. As of May 2007 over 40.3 Million people worldwide are living with HIV/AIDS. To see the "AIDS Clock" visit http://www.unfpa.org/aids_clock/index.html.

According to the Center for Disease Control (CDC) there are 1.185 million people with HIV/AIDS in the U.S.—25% of them unaware of their infection. About 42,000 new cases appear each year. At any one time 25 out of every 100,000 New Yorkers have the HIV virus.

America's African American and Hispanic communities have been disproportionately affected by HIV/AIDS. Currently 50% of new HIV and 50% of new AIDS diagnoses are in African Americans. Of newly infected women, 64% are black, 18% are white and 18% are Hispanic.

What is HIV?

HIV (human immunodeficiency virus) is the virus that causes AIDS (acquired immune deficiency syndrome). HIV weakens a person's immune system. Specifically HIV attacks and destroys a type of white blood cell called a CD4 cell. This cell's main function is to fight disease. When a person's CD4 cell count gets low they become more susceptible to disease. Your immune system plays two important roles: first, it protects you against infection and second, it protects you against developing cancer. People with HIV generally go on to develop full blown AIDS, though treatment can forestall this progress for many years. Those with AIDS most often die of infections or cancers.

What is AIDS?

People with HIV are said to develop AIDS when:

  • They develop certain infections called opportunistic infections. These are infections resulting from common everyday bacteria and spores that most healthy people can normally resist. Examples include certain pneumonia, thrush or recurrent childhood infections.
  • They develop certain cancers such as Kaposi's sarcoma and non-Hodgkin's lymphoma
  • When their CD4 count is less than 200.

What is a CD4 cell?

The CD4 cells are a certain type of white blood cell also called T-cells. HIV attacks these types of cells and uses them to make more copies of HIV. In doing so, the CD4 cell becomes unable to do its job of protecting the body. At first, the body can make more of these T-cells but eventually the body can't keep up and the number of working T-cells decreases. This weakens the immune system and leaves the body at risk for different types of infections.

If left untreated, 90% of HIV-infected individuals develop AIDS and die—about 10% will remain healthy for many years without noticeable symptoms. The development of new medications, called anti-retrovirals, increases life expectancy and improves quality of life so that HIV-infected individuals can lead normal productive lives with near normal life expectancy.

A person gets HIV when an infected person's body fluids (blood, semen, fluids from the vagina or breast) enter his or her blood stream. The virus can enter the blood through linings of the mouth, anus or sex organs (penis and vagina), or through broken skin. Both men and women can spread HIV. Moreover, someone with HIV can feel fine and still give the virus to others.

There are 3 major routes of transmission of HIV. They are:

  • Unprotected sexual intercourse (vaginal, oral or anal)
  • Contaminated needles
  • Transmission from an infected mother to her baby at birth or through breast milk.

Fortunately, in the United States, HIV transmission through blood transfusions has been virtually eliminated though this remains a problem in underdeveloped countries.

The years that followed the discovery of HIV/AIDS were years of hysteria during which those infected with HIV were marginalized. The disease itself was the subject of unfounded rumors. Just to be clear, you cannot get HIV from:

  • Touching or hugging someone who has HIV/AIDS
  • Coming into contact with someone's saliva who has HIV/AIDS
  • Public bathrooms or swimming pools
  • Sharing cups and utensils with someone who has HIV/AIDS.

Can HIV/AIDS be cured?

No. The past decade has seen tremendous strides in helping those affected with HIV manage their disease and lead longer and healthier lives. But there is no known cure at this time for the disease.

HIV Testing

The best way to be certain if you have HIV is to take a blood test. Your blood test results are kept absolutely confidential. In fact they are not sent to the lab with your name, but instead a number is assigned to your blood specimen (anonymous testing). A negative test means that no signs of HIV were found in your blood.

Why should I get HIV testing?

There are many reasons to get an HIV test. Here are just a few:

  • If your test it negative it will put your mind at ease.
  • If your test is positive 
    • Your doctor will want you to start antiretroviral medications (see "HAART" below) to help slow the progression of the infection
    • A health care provider can monitor your health.
    • If you do fall ill, knowing your HIV status in advance will help your health care provider interpret any signs or symptoms you may develop.
    • If you know you are HIV positive you can protect other people.
    • If you know you are HIV positive it may affect your future decisions.

How can I tell if I have the virus that causes AIDS?

People with HIV may look and feel healthy. Many do not even know they have the virus, but they can still infect others through blood-to-blood or sexual contact. Typically, a blood test will show whether you have antibodies to HIV (the virus that causes AIDS). If you have HIV antibodies, it is assumed that you have the HIV infection. It can take up to two weeks to get these results. But now there is a faster test with results in as little as 20 minutes. Go to http://www.achcrochester.org/hiv.php to learn more about HIV testing.

Who should be tested?

Our current recommendations are that people who engage in risky behaviors be tested. This includes:

  • Unprotected intercourse in multiple short term relationships
  • Unprotected intercourse with a partner who is suspected of having other sexual partners
  • I.V. drug users
  • People who share needles

Additionally, all pregnant women should be tested for HIV infection.

If I have HIV will I get AIDS?

People with HIV are said to be "infected" with HIV. As of 1992 scientists estimated that about half of people who become infected with HIV will develop AIDS within 10 years. However, with newer treatments the pace of the disease can be slowed down dramatically in many individuals.

How is HIV Treated? How can I prevent HIV from progressing to AIDS?

There was a time when HIV was considered a death sentence. Today, however, there are a variety of treatments which can retard the progression of the disease and in some cases stop altogether the progression of HIV infection.

After HIV infection is confirmed your doctor will start you on a drug regimen consisting of several drugs: combination of different types of anti-HIV drugs sometimes called HAART (highly-active-retroviral therapy). These drugs must be taken at exactly the right time each day.

You can help prolong your own life by taking good care of yourself and insisting on good medical care from providers who are experienced in treating HIV infection. It is absolutely essential to be consistent about taking your HIV medications as prescribed.

What is the outlook for someone with HIV or AIDS?

The majority of people with HIV who take care of themselves and adhere to their drug regimens can expect to live long and healthy lives. No one can give you a precise answer to the question of "how long do I have?" That said, however, our ever increasing knowledge and treatments offer tremendous hope to those who test positive. HIV is no longer a death sentence.

How can I get more information?

Our best local resource is the

AIDS Community Health Center
At 87 North Clinton Avenue Suite #4
Rochester, NY 14604
585 244-9000. You can visit them at http://www.achcrochester.org/history.php

You can also get information at the CDC National AIDS Hotline: 1-8000-CDC-INFO (232-4636)


Pelvic Inflammatory Disease (PID)


Unlike the other sexually transmitted diseases discussed in this chapter, pelvic inflammatory disease (PID) does not refer to a single bacteria or viral infection. Instead, pelvic inflammatory disease is generally caused by a variety of sexually-transmitted bacteria that can cause acute infection of the upper genital tract—the uterus, fallopian tubes and ovaries as well as other intra-abdominal structures. These bacteria include some you may have heard of—chlamydia and gonorrhea—as well as one's you're probably unfamiliar with—anaerobic streptococci, enterococcus, Klebsiella and E.coli. When infection is confined to the uterus the condition is called endometritis. Infections that involve the fallopian tubes are called salpingitis and ones that involve the ovaries are called oophoritis. Frequently these infections coexist. PID can also involve neighboring pelvic structures including the bowel or upper abdominal structures such as the liver (perihepatitis). Chronic pelvic infections can result in a tubo-ovarian abscess, which is a serious infection often requiring the surgical removal of the tubes and ovaries and even the uterus. Lastly, not all pelvic inflammatory disease is called by sexually transmitted bacteria—some are the result of severe endometriosis, pelvic surgery or even related to diseases of the bowel such as Crohn's disease and chronic appendicitis.

How common is pelvic inflammatory disease?

The National Ambulatory Medical Care Survey estimated that the number of cases of PID in women ages 15-44 was nearly 170,000 in 2003. This represented a decrease of nearly 20,000 cases from the previous year. About 70,000 women per year are hospitalized for acute PID. The numbers are decreasing primarily because of more aggressive screening for chlamydia, one of the major culprits in pelvic inflammatory disease.

What can happen if I get pelvic inflammatory disease?

The major problems associated with pelvic inflammatory disease are infertility, tubal pregnancies and chronic pelvic pain. About 8% of women who have had PID once become infertile. Another 20% will develop chronic pelvic pain.

What are the symptoms of acute pelvic inflammatory disease?

Acute pelvic inflammatory disease can happen after sexual intercourse with an infected partner. Your partner may not even be aware that he is carrying the infection. The symptoms often include fever, chills, lower abdominal bilateral (both the right and left sided) pain, headaches and generalized muscle aches that may or may not be associated with a vaginal discharge. The symptoms will generally force you to seek medical attention. In other cases the symptoms may be more subtle. Some women experience pain with intercourse.

Can acute pelvic inflammatory disease be treated? Is it curable?

The answer to both of these questions is yes. If you contact your health care provider he or she will conduct several tests which may include a complete blood count (CBC), cervical cultures and perhaps a pelvic ultrasound examination. The treatment generally involves a course of oral antibiotics. In severe cases you may be admitted to the hospital to receive intravenous antibiotics. If the infection is treated early in its course damage to the fallopian tubes and ovaries can be prevented and the disease will not prevent a threat to your future fertility. If the diagnosis is delayed the disease can progress to a chronic form which will may cause damage to the fallopian tubes and result in infertility and chronic pelvic pain.

Who is at risk for PID?

The risk factors include women who

  • are less than 25 years old
  • are less than 17 years old when they first become sexually active
  • who don't use condoms
  • who have a new partner
  • have multiple partners
  • have a prior history of PID
  • have tested positive for chlamydia, gonorrhea or bacterial vaginosis

How is the diagnosis of pelvic inflammatory disease made?

In general the diagnosis of pelvic inflammatory disease is what's known as a "clinical diagnosis". To be blunt, the diagnosis is in-exact and imperfect. Why? Given the current state of technology the most precise method of diagnosing pelvic inflammatory disease is by a diagnostic laparoscopy. A laparoscopy is a surgical procedure in which a lit fiberoptic telescope is place through a small incision in the abdomen--this requires anesthesia and is not without risks. For that reason we often make the diagnosis of PID when a woman's medical history, physical exam, blood work, cervical cultures and ultrasound findings are consistent with the diagnosis of pelvic inflammatory disease. This method works out well for uncomplicated cases—particularly those that respond quickly to antibiotics. For more complex cases—such as those that involve a pelvic mass, do not respond quickly to antibiotics or when the symptoms and physical exam are equivocal a laparoscopy may be necessary. Fortunately, laparoscopy is rarely required to establish the diagnosis of PID.

How can I avoid pelvic inflammatory disease?

The methods of avoiding PID are common sense methods:

  • Use condoms to protect yourself.
  • Talk to your partner about STDs before beginning a sexual relationship. Find out whether he or she is at risk for having an STD. Consider getting tested for STDs before you initiate sexual contact with each other. Remember that many STDs such as genital herpes, HPV, chlamydia and even many cases of gonorrhea do not cause symptoms. Even HIV may not show up as a positive blood test for up to 6 months following exposure and infection.
  • If you're under the age of 25 or have reason to doubt the fidelity of your partner get cervical cultures even if you're not having symptoms.
  • If you're having multiple sex partners use condoms, get regular cervical cultures and strongly consider a lifestyle change.
  • Avoid sexual contact with anyone who has symptoms of an STD or who has been exposed to an STD and not been treated.
  • Avoid multiple sex partners.

For additional information visit to the following websites:

http://www.webmd.com/a-to-z-guides/Pelvic-Inflammatory-Disease-Topic-Overview

http://women.webmd.com/Women-Medical-Reference/sexual-health-your-guide-to-pelvic-inflammatory-disease


Chlamydia


"Chlamydia" – short for chlamydia trachomatis-- is the most common of the sexually-transmitted bacterial pelvic infection in women. It is referred to as the "Silent Epidemic" because it often produces no symptoms—especially in women. About 4 million cases of Chlamydia occur in the U.S. each year and about 1 million are actually reported each year to the Center for Disease Control (CDC). In various populations of individuals between the ages of 18 and 26 approximately 4% will test positive for chlamydia. In African American women that number may be as high as 14%. Chlamydia can produce a serious infection and is responsible for a quarter to half-a-million cases of PID each year in the U.S. and may render women exposed to HIV five-times more likely to become infected.

What are the symptoms of chlamydia?

Chlamydia is often a silent disease—a fact that enables these truculent little bacteria to be widely spread. About 75% of women infected have no symptoms. Almost half of the men infected have no symptoms (such as a penile discharge). When symptoms do occur they generally manifest themselves 1-3 weeks following exposure.

In women the bacteria often infects the cervix and the urethra (the canal from which urine is passed).

The urethral infection may manifest itself with a burning sensation on urination.

The cervical infection may produce the following:

  • No symptoms
  • A white or yellowish discharge that looks unfamiliar
  • Lower abdominal pain
  • Back pain
  • Nausea, vomiting
  • Fever
  • Pain with intercourse
  • Abnormal vaginal bleeding—bleeding between normal menses.

With anal intercourse chlamydia can also infect the rectum causing rectal bleeding, discharge or pain.

Oral genital sex can even produce a pharyngitis (sore throat).

What are the risk factors for getting this infection?

The risk factors are the same as for most STDs and include:

  • Adolescents and young adults
  • Multiple sex partners or a partner with many exposures
  • Inconsistent use of condoms
  • History of prior STDs
  • Lower socioeconomic class

How can I be tested for chlamydia?

There are laboratory tests to diagnose chlamydia. Most often we simply obtain a specimen from the cervix. In other instances tests can be performed on urine.

Can Chlamydia be prevented?

The best way to avoid infection is to abstain from sexual contact or to be in a long-term mutually monogamous relationship with a partner who's been tested and is known to be uninfected.

Other recommendations include

  • Use latex condoms correctly and consistently if the above does not apply to you
  • Have chlamydia screening annually if you are under 25 years of age and sexually active
  • If you have symptoms that include a vaginal discharge, burning during urination or any sore or rash please get evaluated by a medical professional.
  • Notify your recent partners of any STD so that they can be treated as well.
  • Do not resume sex until you and your partner have been re-tested and your tests are negative.

Can chlamydia be cured?

Yes--if it is caught in time! If you have an uncomplicated case of chlamydia (no evidence of pelvic inflammatory disease) a simple course of oral antibiotics should cure you. You will be re-tested to be certain that the infection has cleared. It will be very important, however, that you institute life style changes so that you don't become re-infected. Antibiotic therapy consists of: one of the following:

  • Azithromycin 1 gram orally as a single dose
  • Doxycycline 100 mg twice a day for 7 days
  • Erythromycin 500 mg four times a day for 7 days

Chlamydia as a public health issue

NYS law requires that all positive chlamydia cultures be reported to the local Department of Health. Your sexual contacts will be notified of the need for testing. You should not resume intercourse with your partner until you've both been tested and re-cultured to be certain that you are cured of this infection.

Where can I get more information?

http://www.cdc.gov/std/

http://www.monroecounty.gov/health-diseases.php

STD information and referrals to STD Clinics
CDC-INFO
1-800-CDC-INFO (800-232-4636)
TTY: 1-888-232-6348
In English, en Español


Gonorrhea (GC)


Gonorrhea is a bacterial infection caused by the bacterium Neisseria gonorrhoeae. The CDC estimates that more than 700,000 men and women contract new gonorrheal infections each year in the U.S. Gonorrhea is an important cause of urethritis (infection of the tube that carries urine) in men. In women, gonorrhea can cause a cervicitis (infection of the cervix) as well pelvic inflammatory disease (PID) –a cause of infertility and chronic pelvic pain. Gonorrhea can also cause proctitis (infection of the anus) as a result of anal intercourse, pharyngitis (sore throat) as a result of oral-genital transmission and even infection of the Bartholin's glands and Skene's glands. Compared to other infections the "attack rate" of gonorrhea is very high. The odds of a woman becoming infected with gonorrhea after a single episode of intercourse with an infected man (without the use of a condom) are about 50%.

What are the symptoms of gonorrhea?

For women, the early symptoms of gonorrhea ar often mild and usually appear within 2-10 days after sexual contact with an infected partner. Early symptoms include:

  • Bleeding associated with vaginal intercourse
  • Yellow or blood vaginal discharge

More advanced symptoms may indicate an ascending infection—pelvic inflammatory disease. The symptoms of PID include

  • Fever, chills
  • Vomiting
  • Cramps and pain
  • Bleeding between menstrual periods

What are the risk factors for becoming infected with gonorrhea?

The risk factors for becoming infected with GC are identical to those mentioned above under chlamydial infections.

How can I tell if I have gonorrhea?

The most commonly used method of detecting gonorrhea is by a simple cervical culture. A swab is taken from the cervix and results are often reported within 48 hours.

What is the treatment of gonorrhea?

The treatment of gonorrhea depends on a number of factors. However, the CDC recommends one of the following treatments.

  • Ceftriaxone125 mg given as an intramuscular injection
  • Ciprofloxacin 500 mg orally once
  • Ofloxacin 400 mg orally once
  • Levofloxacin 250 mg orally once
  • Spectinomycin 2 g as an intramuscular injection

Public health issues

Gonorrhea is a reportable disease in every state. Sexual partners of patients diagnosed with gonorrhea at any site who've had contact with the infected patients within the past 2 months should be evaluated and treated.


Syphylis

Syphilis is a sexually transmitted diseases called by a spirochete bacterium known as Treponema pallidum. The first reported outbreak of this disease was in 1494 after which it spread rapidly through Europe. In the 16th century it was known as the "great pox" to distinguish it from smallpox. At various times in history it has been called the "French Disease", the "Italian Disease" and "English Disease". The Russians called the "Polish Disease" and the Arabs called it the "Christian Disease." It was not until 1913 that the etiology of this disease was discovered—a spiral-shaped bacterial called Treponema pallidum.

An estimated 32,000 cases of syphilis were reported in 2002 by the CDC. About a quarter were diagnosed in the primary and secondary stages of the disease and majority occurred in women ages 20-24 years of age.

Prior to modern antibiotics this disease often progressed from an initial ulcer called primary syphilis to a generalized rash, secondary syphilis, and eventually to a debilitating destruction of the brain, tertiary syphilis, that caused paralysis—neurosyphillis.

The tragedy of syphilis is that many of those infected with may not have symptoms for years, yet are at risk for developing the late complications of this disease if not treated.

Primary syphilis

Primary syphilis is marked by the appearance of a painless single sore called a chancre. In some cases, however, there are multiple sores. The latent period—time between the infection and the appearance of the chancre averages 21 days (10 – 90 days). The chancre is usually firm, round and small and appears at the spot on the body where the bacteria entered. Typically the chancre lasts 3-6 weeks and heals on its own without treatment. If treatment is not rendered during this phase the disease progresses.

Secondary syphilis

The stage starts with the development of a generalized rash that begins while the chancre is still present or several weeks later. The rash appears on one or more areas of the body and does not cause itching. Typical sites for the rash of secondary syphilis are the palms of the hands and bottoms of the feet. Sometimes the rash is so faint that it is barely noticed. The rash may be accompanied by fever, chills, swollen lymph nodes, a sore throat and hair loss as well as generalized muscle aches and fatigue. Without treatment the infection progresses to the latent and tertiary stages of the disease.

Tertiary syphilis

During the latent phase of the disease the bacteria is still present though there are no signs or symptoms of the disease. The disease progresses, however and causes damage to the internal organs including brain, nerves, eyes, heart, blood vessels, liver, bones and joints. The phase of the disease is very slowly progressive but eventually causes difficulty in coordination of muscle movements, paralysis, blindness and dementia.

How do people get syphilis?

Syphilis is passed from person to person through direct contact with a chancre (sore). Sores typically occur on the vulva, vagina, anus, rectum, mouth and lips. Additionally, pregnant women may pass this disease onto their babies. Syphilis may cause stillbirth or giving birth to a baby that dies shortly after birth. Untreated babies may develop severe neurological problems.

How is syphilis diagnosed?

The simplest way to diagnose this disease is with a routine blood test. You can request this test from your health care provider.

Can syphilis be treated?

Syphilis is easily treated provided it is diagnosed in its early stages. A single intramuscular injection of penicillin (for those not allergic) will cure syphilis in those who've had it for less than a year. For those who are penicillin-allergic there are other convenient antibiotic remedies. It is important for the disease to be diagnosed early as the treatment will not reverse damage already done by this bacterium.

What's the link between syphilis and HIV?

The presence of sores makes it easy for the treponeme (type of bacterium) to enter the body and become infected with HIV if the woman is exposed. There is an estimated 2 to 5-fold increased risk of acquiring HIV infection when syphilis is present.

Where can I get additional information?

STD information and referrals to STD Clinics
CDC-INFO
1-800-CDC-INFO (800-232-4636)
TTY: 1-888-232-6348
In English, en Español

CDC National Prevention Information Network (NPIN)
P.O. Box 6003
Rockville, MD 20849-6003
1-800-458-5231
1-888-282-7681 Fax
1-800-243-7012 TTY
E-mail:
info@cdcnpin.org

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Bacterial Vaginosis (BV)


Bacterial vaginosis, or BV, is not necessarily a sexually transmitted disease, though sexual activity clearly plays a role for many women. Bacterial vaginosis is the name of a condition in women characterized by a disruption in the balance of bacteria normally found in the vagina. It is present in almost 30% of women in this country ages 14-49 making it the most common cause of vaginal discharge in women of childbearing age. About 50-75% of women with BV don't have any symptoms. Those with symptoms often complain of an unpleasant "fishy smelling" discharge that is more noticeable after intercourse. The discharge, when present is off-white, grey and thin. Rarely, women may complain of burning during urination or itching around the outside of the vagina.

What is BV?

The vaginal flora (microbiologic environment) is made up of many microscopic organisms including various bacteria and yeast. There is a "balance" of organisms with a "normal" percentage of E. Coli, lactobacilli, klebsiella and a host of other microbes that make up the vagina. This balance can be shifted by changing pH (acidity) of the vagina. With bacterial vaginosis there is a shift away from these microorganisms, and in particular, lactobacilli to other organisms such as Mycoplasma hominis, Prevotella species, Bacteroides species, Peptostreptococcus species as well as others. The exact mechanism by which the floral balance changes is uncertain and the role of sexual activity is also unknown.

Who is at risk for getting BV?

The risk factors include new sexual partners, multiple partners, douching and cigarette smoking. It's important to note that BV can happen in women who've never had intercourse. Women can also transmit BV to other women suggesting that oral-genital sex may be an important risk factor.

How is the diagnosis of BV made?

The most common way to diagnose BV is simply to observe a thin, grayish-white discharge that smoothly coats the vaginal walls. The vaginal pH is generally over 4.5 suggesting that the balance of lactobacilli is diminished—as this makes the vagina 'more acidic' thereby lowering its pH. A microscopic analysis also reveals "clue cells" that are present. Cultures taken from the vagina are frequently positive for Gardenerella vaginalis an organism frequently found in women with BV. That said, Gardenerella vaginalism is found in almost half of all women without symptoms of BV.

Implications of BV

It is believed that women with BV have a greater incidence of pre-term delivery with pregnancy. The major implication for women, however, is the presence of a discharge or a "fishy" odor.

BV may be a risk factor for infection with genital herpes, gonorrhea and chlamydia though the exact mechanism of this is unknown.

Treatment

These infections generally respond well to treatment with either metronidazole (taken as a tablet or vaginal gel) or clindamycin. Whether or not your partner will need to be treated is a subject you should discuss with your health care provider.

Summary

In summary, bacterial vaginosis (BV) is not an infection--it is a change in the colonization or flora of the vagina. This change may lead to a foul odor, a discharge or vaginal irritation. It may be sexually acquired, hence its listing in this webpage, but not necessarily. It is associated with multiple sex partners but does not require penile intercourse and has been associated with oral-genital sex. It's implications for your overall health is debated though it clearly plays a role in pregnancy and may play a role in increasing the likelihood of postoperative infections following hysterectomy and even abortions. It is not clear that your partner should be treated if you have BV, though this may be tried if you have recurrences. BV is commonly found in women though often in an asymptomatic form. If you have been diagnosed with BV do not—I repeat do not—go home and confront your sexual partner of infidelity! Ask your health care provider and consult some of these websites for further information.

http://www.healthywomen.org/healthtopics/bacterialvaginosis

http://www.4woman.gov/faq/stdbv.htm


Trichomonas Vaginitis

Trichomonas vaginitis is a common vaginal infection caused by a protozoan known as trichomonas vaginalis. This infection is, with rare exceptions, sexually transmitted. It is often found with other STDs and can be found in the vagina, urethra, cervix, Bartholin's and Skene's glands. Women can acquire this infection from men and other women.

The Center for Disease Control (CDC) estimates that the prevalence of this infection varies from 13% in African American women to a little over 1% in white and Mexican-American women.

Typical signs and symptoms include a foul odor accompanied by a thin greenish to yellowish frothy discharge. This may also be accompanied by vaginal itching, burning on urination, frequent urination, painful intercourse and bleeding after intercourse. Symptoms may occur from 4-30 days after exposure.

The major implications of trichomoniasis are the symptoms of vaginitis (itching and discharge) and urethritis (urinary frequency and burning). Trichomoniasis is also a risk factor for developing infections after hysterectomy and may also play a role in tubal infertility. Another, more recent concern, is that the infection may facilitate transmission of HIV.

The consequences of trichomoniasis are important for pregnant women as it is associated with premature rupture of membranes and preterm delivery.

The diagnosis of trichomonas vaginitis is beyond the scope of this webpage. However, this infection is easily treated with Flagyl (metronidazole).


LYMPHOGRANULOMA VENERUM (LGV)


LGV is a relatively rare sexually transmitted disease that affects lymph notes and is caused by serovars L1, L2, and L3 of the bacterium Chlamyida trachomatis. The infection produces a painless ulcer and may be confused with primary syphilis. The disease is rare in the U.S. with fewer than 600 cases reported annually--far fewer cases are reported in women than in men. LGVis endemic in parts of Africa, India, Southeast Asia, South America and the Caribbean. Recent outbreaks have occurred in Europe

The primary stage of the disease starts out as a painless ulcer at the site where the bacteria gain entrance to the mucous membrane or skin. Typically, in women the initial site of entry is the vaginal wall. The ulcer lasts 3-12 days. While men can easily detect their lesions it often goes unnoticed in women because it is painless and out of site. The lesion heals before the disease enters the secondary stage some 10 – 30 days later.

LGV gains entrance through breaks in the skin and travels through lymphatic channels settling into lymph nodes where it causes the formation of abscesses – also called buboes. If the affected lymph nodes are in the groin it causes the inguinal syndrome. These same abscesses occur in the lymph nodes draining the rectum the rectal syndrome of this disease appears. For a picture of what the lesions look like click on the following link:

http://members.shaw.ca/fartpipe/temp/crap/Bluesky.jpg

The secondary stage is characterized by the spread of the infection to the surrounding lymph nodes along the lymphatic drainage pathways. In women the infection may spread to the cervix (cervicitis), the internal tissues alongside the uterus (perimetritis) or the fallopian tubes (salpingitis). In addition the deep lymph nodes may become infected causing lymphadenitis. About 20% of women will develop a swelling and abscess in their inguinal lymph nodes. This is often accompanied by fever, chills, fatigue and loss of appetite.

If left untreated a tertiary stage follows characterized by permanent scarring may occur in various internal organs leading to infertility, pelvic pain and others symptoms resulting from permanent scarring.


CHANCROID

Chancroid is another rare bacterial infection caused by Haemophilus ducreyi. It is rarely found in the U.S. but frequently found in 3rd world countries among sex workers. It is characterized by a painful ulcer (unlike LGV or syphilis). Most individuals in the U.S. who've contracted chancroid have visited countries where the disease is endemic.

The sore varies in size from 1/8 of an inch to 2 inches in diameter and makes its appearance 1-14 days after exposure to the bacterium. The base of the sore bleeds easily if scraped or traumatized. Unlike genital herpes it occurs as a single lesion. Moreover, a culture for HSV will be negative. It tends to occur on the labia minor in women as well as the opening of the vagina.

The disease is treated with antibiotics and typically responds well once the diagnosis has been made. To learn more about the disease click on one of these websites.

http://www.health.state.ny.us/diseases/communicable/chancroid/fact_sheet.htm

http://www.ashastd.org/learn/learn_chancroid.cfm



"OH MY GOD I HAVE AN OVARIAN CYST!"

Introduction

If you are a woman within the age range of 13 – 50 and you're told that you have an ovarian cyst you need to take a deep breath and stop thinking that you're going to die of ovarian cancer.

Ovarian cysts are common and are one of the leading reasons that women seek help from their gynecologists. Often they produce symptoms of lower abdominal pain. Other symptoms associated with them include distention, abnormal menstrual bleeding or pain during intercourse. However, with the large number of ultrasound examinations, CT scans and MRIs that are performed—often for reasons other than pelvic pain-- we see an increasing number of patients that are referred from their primary care doctors or radiologists that have been told that they have an ovarian cyst or cysts. These women often have no symptoms other than the tremendous anxiety that may have cancer or infertility.

In my last newsletter I talked about the difference between perception and reality—in that particular newsletter (Volume 1, No.2), if you recall, the topics were coffee (it really is good for most women!) and female cancers (no, that's not what most women are going to die of!). The reality of ovarian cysts is that every woman who ovulates gets them—because a cyst is critical to the development of an egg as well as the hormones estrogen and progesterone. Unfortunately, there are some abnormal ovarian cysts but the overwhelming majority of them are benign. Rarely, there are ovarian cancers that occur in this age group—very rarely. The reality is that most ovarian cysts are physiologic and a few are pathologic.

A physiologic cyst is one that serves a purpose in reproductive function—it's where your eggs are made and where the hormones estrogen and progesterone are made. For that reason physiologic ovarian cysts are also called functional ovarian cysts. These cysts appear and disappear as you progress from one menstrual cycle to the next.

Pain sometimes accompanies physiologic ovarian cysts. Cysts occur as part of every menstrual cycle—but most women do not experience pain during every menstrual cycle. The reasons why some cysts cause pain and others don't are complex but here are some of them:

Larger ovarian cysts are more likely to cause pain even though larger ones aren't any more "dangerous" than smaller ones.

Larger cysts may be more likely to "leak" fluid—and that can cause pain

In most cases, however, it simply isn't clear why some women experience pain some of the time but not at others.

Pathologic cysts serve no reproductive or hormonal function; all they do is to scare you. In most cases they need to be removed. Usually an ultrasound examination can tell the difference between a physiologic (functional) ovarian cyst and a pathologic cyst (one that should be removed).

How do physiologic (functional) ovarian cysts occur?


As I already said these are also called functional ovarian cysts—because they serve a function! Here's how they occur. In the early part of your menstrual cycle—beginning with the onset of your period—your eggs are already maturing and being selected for you next ovulation. The next ovulation often occurs 14 days after the onset of your period. During that 14 day stretch from the first day of your period until ovulation several small cysts start to grow on your ovary. These look like tiny little balloon structures and vary from ¼ inch to an inch in diameter. During a typical cycle your ovaries may grow several of these cysts—as many as a dozen—but only 1 or 2 will actually mature enough to ovulate and produce a mature egg ready for ovulation. The fluid within this little "balloon" contains estrogen. So you see that the cyst in the early part of your menstrual cycle serves at least two functions—first, it's where your eggs grow and second it's where estrogen production occurs.

After these cysts get to a certain size—around an inch in diameter—they rupture. This is called ovulation!

Notice the hole to the right portion of the ovary. This is where ovulation occurred and the egg passed into the fallopian tube. That's why we often refer to physiologic (functional) ovarian cysts that occur prior to ovulation as "ovulation cysts". These cysts can be painful as many women experience some pain as these cysts are enlarging and getting ready to "pop" (ovulate).

After ovulation, something miraculous happens. The very cyst where the egg grew—which is now collapsed and empty for a short while—starts to fill in with blood vessels and that "ovulation" cyst starts producing cholesterol--you see, a certain amount of cholesterol isn't a bad thing!

The cholesterol undergoes a chemical change and becomes the hormone progesterone. Progesterone is made in another type of physiologic cyst called a corpus luteum cyst. Corpus is the Greek work for "body" and "lutea" means "yellow". These cysts are often yellow in color because of the cholesterol (which is a fat) in them. The purpose of progesterone is to nurture an early pregnancy. If a pregnancy doesn't occur during that cycle the cyst dissolves and your next menstrual period starts about 2 weeks after ovulation and about 4 weeks since the onset of your previous menstrual period. Occasionally, these corpus luteum cysts can grow quite large—3 to 4 inches in diameter. At that size they're bigger than your uterus. They can be quite painful and scary—especially if at the same time you're worrying about something like cancer! The good news is that these cysts go away by their selves. It may take a week or two but they disappear as your body is getting ready for the next cycle.

Cysts are easily seen on ultrasound examination—and that's how we diagnose them. It's quite simple to see them. On ultrasound exam solid structures (like your uterus which is mostly muscle) show up in different shades of grey. Cysts are filled with fluid and all fluids show up on ultrasound as black.


There are at least 5 cysts (some small and one big one).
The cysts are black in appearance. The intervening grey structure is the rest of the ovary.

Notice how this ovary is made up of several small "black balloons" with one dominant one—the largest one. These are all individual cysts—however, only the largest of these is likely to "ovulate" and produce an egg, while the others shrivel (a process called atresia). In this case one can easily count at least 5 cystic cavities (follicles) on this single ovary. From experience I can tell you with great certainty that this most likely represents an ovulation cyst—one that occurs just prior to ovulation. Remember that ovulation cysts (also called follicular cysts) produce two things: eggs and estrogen.


Now here's an example of the second type of functional ovarian cyst—the corpus luteum cyst. We see that the "balloon" is still black but it has a fine mottled appearance as if there are small cobwebs within it.

The point is that both of these kinds of cysts happen in every woman virtually every cycle during her reproductive years---even if she is taking oral contraceptives. Corpus luteum cysts last about 14 days before they dissolve and allow the next cycle to begin. Should pregnancy occur, the corpus luteum cyst, which produces progesterone, will sustain the early pregnancy throughout the first trimester (12 weeks) and becomes known as the corpus luteum of pregnancy.

So let's review:

Cysts can be either:

Physiologic (also called functional) one kind occurs prior to ovulation and is called an ovulation or follicular cyst. Another kind occurs after ovulation and is called a corpus luteum cyst

WITH FEW EXCEPTIONS PHYSIOLOGIC CYTS GO AWAY ON THEIR OWN AND DON'T REQUIRE SURGERY.

Or Pathologic – these are abnormal and generally do not go away by their selves.

What is a pathologic ovarian cyst?

These cysts don't serve a function--the majority of them occur in women under 50 and are benign.
There are many different kinds of pathologic ovarian cysts – most are benign.
You may have heard of some of these.

Endometriomas. These cysts form in women who have endometriosis—a whole other subject for a future newsletter. Endometriosis occurs when tissue that normally lines the inside of the uterus grows outside the uterus—often on the surface of the uterus, bowel, bladder or ovaries. When the tissue becomes attached to the ovary it tends to grow rapidly and can produce large ovarian cysts. These cysts can produce pain, infertility and even make it difficult to have sex.

Cystadenomas. These cysts form from cells on the outer surface of the ovary. They are often filled with a watery fluid or thick, sticky gel. They can become large and cause pain. Most often, however, these cysts do not cause pain unless they twist or rupture.

Dermoid cysts. These cysts contain many types of cells. They may be filled with hair, teeth, and other tissues that become part of the cyst. They too are generally painless but can become large and often show up on either a pelvic examination or a routine ultrasound.

Polycystic ovaries. These cysts are caused when eggs mature within the "little balloons" but are not released. The cycle then repeats. The sacs continue to grow and many cysts form. Women with polycystic ovaries often have other issues which may include irregular periods and infertility.

What are the symptoms of an ovarian cyst?

Symptoms of ovarian cysts (physiologic or pathologic) include:

  • pressure, swelling in the abdomen
  • pelvic pain
  • dull ache in the lower back and thighs
  • problems passing urine completely
  • pain during sex
  • pain during your period
  • abnormal bleeding
  • breast tenderness
  • nausea and vomiting

What do I do if I'm told I have an ovarian cyst?

The best thing to do is try and talk to your health care provider as soon as possible. Generally, she or he will assure you that your cyst is most likely benign and often you'll be given a "best guess" that the cyst is functional (physiologic) and will likely disappear on its own. It's easy to say don't panic---but try not to. Remember that the vast majority of cysts between the ages of 13 and 50 are normal structures that you make in the process of ovulation and hormone production. Most ovarian cysts will not cause future problems though they may certainly cause inconvenience. Only a very small number of them will require intervention—surgery.


 

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